Jessica Severin
Overview
Explore the profile of Jessica Severin including associated specialties, affiliations and a list of published articles.
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44
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5871
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Recent Articles
1.
Nobusada T, Yip C, Agrawal S, Severin J, Abugessaisa I, Hasegawa A, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D419-D424.
PMID: 39592010
The FANTOM web resource (https://fantom.gsc.riken.jp/) has been a unique resource for studying mammalian genomes, which is built on the research activities conducted in the international collaborative project FANTOM (Functional ANnoTation...
2.
Agrawal S, Buyan A, Severin J, Koido M, Alam T, Abugessaisa I, et al.
PLoS One
. 2024 May;
19(5):e0295971.
PMID: 38709794
The human genome is pervasively transcribed and produces a wide variety of long non-coding RNAs (lncRNAs), constituting the majority of transcripts across human cell types. Some specific nuclear lncRNAs have...
3.
Severin J, Agrawal S, Ramilowski J, Deviatiiarov R, Shin J, Carninci P, et al.
NAR Genom Bioinform
. 2023 Aug;
5(3):lqad075.
PMID: 37608799
In the genomic era, data dissemination and visualization is an integral part of scientific publications and research projects involving international consortia producing massive genome-wide data sets, intra-organizational collaborations, or individual...
4.
Yip C, Hon C, Yasuzawa K, Sivaraman D, Ramilowski J, Shibayama Y, et al.
Cell Rep
. 2022 Dec;
41(13):111893.
PMID: 36577377
Within the scope of the FANTOM6 consortium, we perform a large-scale knockdown of 200 long non-coding RNAs (lncRNAs) in human induced pluripotent stem cells (iPSCs) and systematically characterize their roles...
5.
Pascarella G, Hon C, Hashimoto K, Busch A, Luginbuhl J, Parr C, et al.
Cell
. 2022 Jul;
185(16):3025-3040.e6.
PMID: 35882231
Non-allelic recombination between homologous repetitive elements contributes to evolution and human genetic disorders. Here, we combine short- and long-DNA read sequencing of repeat elements with a new bioinformatics pipeline to...
6.
Grapotte M, Saraswat M, Bessiere C, Menichelli C, Ramilowski J, Severin J, et al.
Nat Commun
. 2022 Mar;
13(1):1200.
PMID: 35232988
No abstract available.
7.
Hashimoto M, Saito Y, Nakagawa R, Ogahara I, Takagi S, Takata S, et al.
Nat Cancer
. 2022 Feb;
2(3):340-356.
PMID: 35121960
Aggressive therapy-resistant and refractory acute myeloid leukemia (AML) has an extremely poor outcome. By analyzing a large number of genetically complex and diverse, primary high-risk poor-outcome human AML samples, we...
8.
Grapotte M, Saraswat M, Bessiere C, Menichelli C, Ramilowski J, Severin J, et al.
Nat Commun
. 2021 Jun;
12(1):3297.
PMID: 34078885
Using the Cap Analysis of Gene Expression (CAGE) technology, the FANTOM5 consortium provided one of the most comprehensive maps of transcription start sites (TSSs) in several species. Strikingly, ~72% of...
9.
Gazova I, Lefevre L, Bush S, Clohisey S, Arner E, de Hoon M, et al.
Front Cell Dev Biol
. 2020 Jul;
8:498.
PMID: 32719792
The response of the human acute myeloid leukemia cell line THP-1 to phorbol esters has been widely studied to test candidate leukemia therapies and as a model of cell cycle...
10.
Ramilowski J, Yip C, Agrawal S, Chang J, Ciani Y, Kulakovskiy I, et al.
Genome Res
. 2020 Jul;
30(7):1060-1072.
PMID: 32718982
Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down...