Jessica K R Boult
Overview
Explore the profile of Jessica K R Boult including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
785
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Recent Articles
1.
Nimalasena S, Anbalagan S, Box C, Yu S, Boult J, Bush N, et al.
BJC Rep
. 2024 Oct;
2(1):78.
PMID: 39391329
Background: KORTUC (0.5% hydrogen peroxide (HO) in 1% sodium-hyaluronate) releases cytotoxic levels of HO in tissues after intratumoural injection. High levels of tumour control after radiotherapy plus KORTUC are reported...
2.
Reeves E, Li J, Zormpas-Petridis K, Boult J, Sullivan J, Cummings C, et al.
Mol Oncol
. 2023 Apr;
17(6):1076-1092.
PMID: 37081807
Hyaluronan (HA) is a key component of the dense extracellular matrix in breast cancer, and its accumulation is associated with poor prognosis and metastasis. Pegvorhyaluronidase alfa (PEGPH20) enzymatically degrades HA...
3.
Maczynska J, Raes F, Da Pieve C, Turnock S, Boult J, Hoebart J, et al.
BMC Med
. 2022 May;
20(1):179.
PMID: 35505318
No abstract available.
4.
Maczynska J, Raes F, Da Pieve C, Turnock S, Boult J, Hoebart J, et al.
BMC Med
. 2022 Jan;
20(1):16.
PMID: 35057796
Background: Surgical resection followed by chemo-radiation postpones glioblastoma (GBM) progression and extends patient survival, but these tumours eventually recur. Multimodal treatment plans combining intraoperative techniques that maximise tumour excision with...
5.
Izquierdo E, Carvalho D, Mackay A, Temelso S, Boult J, Pericoli G, et al.
Cancer Discov
. 2021 Nov;
12(3):712-729.
PMID: 34737188
Significance: We report alterations in the MAPK pathway in DIPGs to confer initial sensitivity to targeted MEK inhibition. We further identify for the first time the mechanism of resistance to...
6.
Zormpas-Petridis K, Poon E, Clarke M, Jerome N, Boult J, Blackledge M, et al.
Cancer Res
. 2020 Jun;
80(16):3424-3435.
PMID: 32595135
Noninvasive early indicators of treatment response are crucial to the successful delivery of precision medicine in children with cancer. Neuroblastoma is a common solid tumor of young children that arises...
7.
Clarke M, Mackay A, Ismer B, Pickles J, Tatevossian R, Newman S, et al.
Cancer Discov
. 2020 Apr;
10(7):942-963.
PMID: 32238360
Infant high-grade gliomas appear clinically distinct from their counterparts in older children, indicating that histopathologic grading may not accurately reflect the biology of these tumors. We have collected 241 cases...
8.
Li J, Zormpas-Petridis K, Boult J, Reeves E, Heindl A, Vinci M, et al.
Cancer Res
. 2019 Oct;
79(22):5874-5883.
PMID: 31604713
Increased stiffness in the extracellular matrix (ECM) contributes to tumor progression and metastasis. Therefore, stromal modulating therapies and accompanying biomarkers are being developed to target ECM stiffness. Magnetic resonance (MR)...
9.
Al-Saffar N, Troy H, Wong Te Fong A, Paravati R, Jackson L, Gowan S, et al.
Br J Cancer
. 2018 Nov;
119(9):1118-1128.
PMID: 30377337
Background: AKT is commonly overexpressed in tumours and plays an important role in the metabolic reprogramming of cancer. We have used magnetic resonance spectroscopy (MRS) to assess whether inhibition of...
10.
Baker L, Sikka A, Price J, Boult J, Lepicard E, Box G, et al.
Front Oncol
. 2018 Aug;
8:271.
PMID: 30083516
Overexpression of EGFR is a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). Patients with HNSCC who respond to EGFR-targeted tyrosine kinase inhibitors (TKIs) eventually develop acquired...