Jessica K Mazalo
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Explore the profile of Jessica K Mazalo including associated specialties, affiliations and a list of published articles.
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4
Citations
52
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Recent Articles
1.
Mazalo J, Tay S, Kempe D, Biro M
Biophys J
. 2024 Feb;
123(15):2328-2342.
PMID: 38327056
T cells migrate constitutively with a polarized morphology, underpinned by signaling compartmentalization and discrete cytoskeletal organizations, giving rise to a dynamic and expansive leading edge, distinct from the stable and...
2.
Govendir M, Kempe D, Sianati S, Cremasco J, Mazalo J, Colakoglu F, et al.
Dev Cell
. 2022 Sep;
57(18):2237-2247.e8.
PMID: 36113483
Cytotoxic T lymphocytes (CTLs) lyse target cells by delivering lytic granules that contain the pore former perforin to the cytotoxic immunological synapse. Here, we establish that opposing cytoskeletal forces drive...
3.
Cavanagh H, Kempe D, Mazalo J, Biro M, Endres R
J R Soc Interface
. 2022 May;
19(190):20220081.
PMID: 35537475
T cells use sophisticated shape dynamics (morphodynamics) to migrate towards and neutralize infected and cancerous cells. However, there is limited quantitative understanding of the migration process in three-dimensional extracellular matrices...
4.
Galeano Nino J, Pageon S, Tay S, Colakoglu F, Kempe D, Hywood J, et al.
Elife
. 2020 Oct;
9.
PMID: 33046212
Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL populations...