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Jessica Hauschild

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Articles 36
Citations 580
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Recent Articles
1.
Dyshlovoy S, Mansour W, Ramm N, Hauschild J, Zhidkov M, Kriegs M, et al.
Sci Rep . 2024 May; 14(1):11788. PMID: 38783016
Fascaplysin is a red cytotoxic pigment with anticancer properties isolated from the marine sponge Fascaplysinopsis sp. Recently, structure-activity relationship analysis reported by our group suggested that selective cytotoxicity of fascaplysin...
2.
Menchinskaya E, Dyshlovoy S, Venz S, Jacobsen C, Hauschild J, Rohlfing T, et al.
Mar Drugs . 2024 Jan; 22(1). PMID: 38248645
Despite recent advances in the treatment of metastatic castration-resistant prostate cancer (CRPC), treatment is inevitably hampered by the development of drug resistance. Thus, new drugs are urgently needed. We investigated...
3.
Dyshlovoy S, Hauschild J, Venz S, Krisp C, Kolbe K, Zapf S, et al.
Mol Pharm . 2023 Sep; 20(10):4994-5005. PMID: 37733943
Rhizochalinin (Rhiz) is a recently discovered cytotoxic sphingolipid synthesized from the marine natural compound rhizochalin. Previously, Rhiz demonstrated high in vitro and in vivo efficacy in various cancer models. Here,...
4.
Leshchenko E, Antonov A, Borkunov G, Hauschild J, Zhuravleva O, Khudyakova Y, et al.
Mar Drugs . 2023 Mar; 21(3). PMID: 36976227
Five new β-resorcylic acid derivatives, 14-hydroxyasperentin B (), β-resoantarctines A-C (, , ) and 8-dehydro-β-resoantarctine A (), together with known 14-hydroxyasperentin (5'-hydroxyasperentin) (), were isolated from the ethyl acetate extract...
5.
Dyshlovoy S, Zhuravleva O, Hauschild J, Busenbender T, Pelageev D, Yurchenko A, et al.
Mar Drugs . 2023 Jan; 21(1). PMID: 36662227
Marine fungi serve as a valuable source for new bioactive molecules bearing various biological activities. In this study, we report on the isolation of a new indole diketopiperazine alkaloid deoxy-14,15-dehydroisoaustamide...
6.
Dyshlovoy S, Shubina L, Makarieva T, Guzii A, Hauschild J, Strewinsky N, et al.
Mar Drugs . 2022 Dec; 20(12). PMID: 36547885
Two new guanidine alkaloids, batzelladines O () and P (), were isolated from the deep-water marine sponge The structures of these metabolites were determined by NMR spectroscopy, mass spectrometry, and...
7.
von Amsberg G, Zilles M, Mansour W, Gild P, Alsdorf W, Kaune M, et al.
Int J Mol Sci . 2022 Dec; 23(23). PMID: 36499277
Significant progress has been achieved in the treatment of metastatic castration-resistant prostate cancer (mCRPC). However, results in patients with aggressive variant prostate cancer (AVPC) have been disappointing. Here, we report...
8.
Leshchenko E, Antonov A, Dyshlovoy S, Berdyshev D, Hauschild J, Zhuravleva O, et al.
J Nat Prod . 2022 Nov; 85(12):2746-2752. PMID: 36413729
New meroterpenoids, meroantarctines A-C (-), with unique 6/5/6/6, 6/5/6/5/6, and 6/5/6/5 polycyclic systems were isolated from the alga-derived fungus KMM 4685. Their structures were elucidated by spectroscopic methods, X-ray diffraction,...
9.
Dyshlovoy S, Busenbender T, Hauschild J, Girich E, Kriegs M, Hoffer K, et al.
Mar Drugs . 2022 Oct; 20(10). PMID: 36286421
N-methylpretrichodermamide B (NB) is a biologically active epidithiodiketopiperazine isolated from several strains of the algae-derived fungus sp. Recently, we reported the first data on its activity in human cancer cells...
10.
Dyshlovoy S, Shubina L, Makarieva T, Hauschild J, Strewinsky N, Guzii A, et al.
Sci Rep . 2022 Aug; 12(1):13570. PMID: 35945234
Spongian diterpenes are a group of marine natural compounds possessing various biological activities. However, their anticancer activity is still poorly studied and understood. We isolated six spongian diterpenes from the...