Jessica E Kenison
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Explore the profile of Jessica E Kenison including associated specialties, affiliations and a list of published articles.
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22
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1910
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Recent Articles
1.
Lee H, Rone J, Li Z, Faust Akl C, Shin S, Lee J, et al.
Nature
. 2024 Jun;
631(8020):E8.
PMID: 38907058
No abstract available.
2.
Lee H, Rone J, Li Z, Faust Akl C, Shin S, Lee J, et al.
Nature
. 2024 Mar;
627(8005):865-872.
PMID: 38509377
Disease-associated astrocyte subsets contribute to the pathology of neurologic diseases, including multiple sclerosis and experimental autoimmune encephalomyelitis (EAE), an experimental model for multiple sclerosis. However, little is known about the...
3.
Lee H, Rone J, Li Z, Faust Akl C, Shin S, Lee J, et al.
bioRxiv
. 2024 Jan;
PMID: 38260616
Astrocytes play important roles in the central nervous system (CNS) physiology and pathology. Indeed, astrocyte subsets defined by specific transcriptional activation states contribute to the pathology of neurologic diseases, including...
4.
Kenison J, Stevens N, Quintana F
Nat Rev Immunol
. 2023 Dec;
24(5):338-357.
PMID: 38086932
The development of therapeutic approaches for the induction of robust, long-lasting and antigen-specific immune tolerance remains an important unmet clinical need for the management of autoimmunity, allergy, organ transplantation and...
5.
Sanmarco L, Rone J, Polonio C, Lahore G, Giovannoni F, Ferrara K, et al.
Nature
. 2023 Aug;
620(7975):881-889.
PMID: 37558878
Dendritic cells (DCs) have a role in the development and activation of self-reactive pathogenic T cells. Genetic variants that are associated with the function of DCs have been linked to...
6.
Sanmarco L, Rone J, Polonio C, Giovannoni F, Lahore G, Ferrara K, et al.
bioRxiv
. 2023 Mar;
PMID: 36993446
Dendritic cells (DCs) control the generation of self-reactive pathogenic T cells. Thus, DCs are considered attractive therapeutic targets for autoimmune diseases. Using single-cell and bulk transcriptional and metabolic analyses in...
7.
Sanmarco L, Chao C, Wang Y, Kenison J, Li Z, Rone J, et al.
Nature
. 2022 Oct;
611(7937):801-809.
PMID: 36266581
Genome-wide association studies have identified risk loci linked to inflammatory bowel disease (IBD)-a complex chronic inflammatory disorder of the gastrointestinal tract. The increasing prevalence of IBD in industrialized countries and...
8.
Kenison J, Wang Z, Yang K, Snyder M, Quintana F, Sherr D
Proc Natl Acad Sci U S A
. 2021 May;
118(19).
PMID: 33941684
Immune checkpoint inhibitors represent some of the most important cancer treatments developed in the last 20 y. However, existing immunotherapy approaches benefit only a minority of patients. Here, we provide...
9.
Rothhammer V, Kenison J, Li Z, Tjon E, Takenaka M, Chao C, et al.
Neurol Neuroimmunol Neuroinflamm
. 2021 Jan;
8(2).
PMID: 33408169
Objective: MS is an autoimmune demyelinating disease of the CNS, which causes neurologic deficits in young adults and leads to progressive disability. The aryl hydrocarbon receptor (AHR), a ligand-activated transcription...
10.
Levy O, Rothhammer V, Mascanfroni I, Tong Z, Kuai R, De Biasio M, et al.
J Mol Med (Berl)
. 2021 Jan;
99(5):663-671.
PMID: 33398468
Mesenchymal stem cells (MSCs) are promising candidates for the development of cell-based drug delivery systems for autoimmune inflammatory diseases, such as multiple sclerosis (MS). Here, we investigated the effect of...