Jessica C Sacher
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Explore the profile of Jessica C Sacher including associated specialties, affiliations and a list of published articles.
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13
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254
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Recent Articles
1.
Kim M, Suh G, Cullen G, Perez Rodriguez S, Dharmaraj T, Chang T, et al.
J Clin Invest
. 2025 Mar;
135(5).
PMID: 40026251
Bacteriophage (phage) therapy has emerged as a promising solution to combat the growing crisis of multidrug-resistant (MDR) infections. There are several international centers actively engaged in implementation of phage therapy,...
2.
Sacher J, Zheng J
Phage (New Rochelle)
. 2022 Sep;
2(4):156-169.
PMID: 36159885
The phage field is clearly growing around the world, but no one had compiled a bird's eye view of the phages being collected and the phage research and development work...
3.
Sacher J, Zheng J, Lin R
Phage (New Rochelle)
. 2022 Sep;
3(2):112-115.
PMID: 36157289
Phage Directory has recently partnered with Phage Australia to help optimize Australia's data-centric standardized approach to personalized phage therapy. Here is a behind-the-scenes look at the genesis of Phage Australia,...
4.
Sacher J, Javed M, Crippen C, Butcher J, Flint A, Stintzi A, et al.
Viruses
. 2021 Oct;
13(10).
PMID: 34696385
is a Gram-negative foodborne pathogen that causes diarrheal disease and is associated with severe post-infectious sequelae. Bacteriophages (phages) are a possible means of reducing colonization in poultry to prevent downstream...
5.
Lin R, Sacher J, Ceyssens P, Zheng J, Khalid A, Iredell J
Curr Opin Biotechnol
. 2021 Feb;
68:221-230.
PMID: 33581425
After a century of use in human infection, the preparation and administration of therapeutic bacteriophages (phages) still relies on ad hoc partnerships of researchers, biotech companies, clinicians and regulators. There...
6.
Sacher J, Shajahan A, Butcher J, Patry R, Flint A, Hendrixson D, et al.
Front Microbiol
. 2020 Apr;
11:397.
PMID: 32265863
Many bacterial pathogens display glycosylated surface structures that contribute to virulence, and targeting these structures is a viable strategy for pathogen control. The foodborne pathogen expresses a vast diversity of...
7.
Irons J, Sacher J, Szymanski C, Downs D
Front Microbiol
. 2019 Sep;
10:2058.
PMID: 31555246
is the leading bacterial cause of acute gastroenteritis worldwide and thus significant to public health. primarily lives in the gastrointestinal tracts of poultry and can contaminate meat during processing. Despite...
8.
Crippen C, Lee Y, Hutinet G, Shajahan A, Sacher J, Azadi P, et al.
J Virol
. 2019 Sep;
93(23).
PMID: 31511377
Several reports have demonstrated that bacteriophage DNA is refractory to manipulation, suggesting that these phages encode modified DNA. The characterized phages fall into two phylogenetic groups within the : the...
9.
McCallin S, Sacher J, Zheng J, Chan B
Viruses
. 2019 Apr;
11(4).
PMID: 31013833
There is a current unmet medical need for the treatment of antibiotic-resistant infections, and in the absence of approved alternatives, some clinicians are turning to empirical ones, such as phage...
10.
Bacterial AB toxins inhibit the growth of gut bacteria by targeting ganglioside-like glycoconjugates
Patry R, Stahl M, Perez-Munoz M, Nothaft H, Wenzel C, Sacher J, et al.
Nat Commun
. 2019 Mar;
10(1):1390.
PMID: 30918252
The AB toxins cholera toxin (CT) from Vibrio cholerae and heat-labile enterotoxin (LT) from enterotoxigenic Escherichia coli are notorious for their roles in diarrheal disease, but their effect on other...