Jeske J Smink
Overview
Explore the profile of Jeske J Smink including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
15
Citations
385
Followers
0
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Recent Articles
1.
Schubert A, Smink J, Pumberger M, Putzier M, Sittinger M, Ringe J
J Orthop Surg Res
. 2018 Aug;
13(1):209.
PMID: 30134986
Background: The lifetime prevalence of degenerative disc disease is dramatically high. Numerous investigations on disc degeneration have been performed on cells from annulus fibrosus (AF) and nucleus pulposus (NP) of...
2.
Schubert A, Smink J, Arp M, Ringe J, Hegewald A, Sittinger M
Int J Mol Sci
. 2018 Jun;
19(6).
PMID: 29899321
A discrimination of the highly specialised annulus fibrosus (AF) and nucleus pulposus (NP) cells in the mature human intervertebral disc (IVD) is thus far still not possible in a reliable...
3.
Bartz C, Meixner M, Giesemann P, Roel G, Bulwin G, Smink J
J Transl Med
. 2016 Nov;
14(1):317.
PMID: 27846904
Background: Cell-based therapies such as autologous chondrocyte implantation are promising therapeutic approaches to treat cartilage defects to prevent further cartilage degeneration. To assure consistent quality of cell-based therapeutics, it is...
4.
Zscharnack M, Krause C, Aust G, Thummler C, Peinemann F, Keller T, et al.
J Transl Med
. 2015 May;
13:160.
PMID: 25990108
Background: The clinical development of advanced therapy medicinal products (ATMPs), a new class of drugs, requires initial safety studies that deviate from standard non-clinical safety protocols. The study provides a...
5.
Begay V, Smink J, Loddenkemper C, Zimmermann K, Rudolph C, Scheller M, et al.
J Mol Med (Berl)
. 2014 Nov;
93(1):39-49.
PMID: 25401168
Unlabelled: Two long and one truncated isoforms (termed LAP*, LAP, and LIP, respectively) of the transcription factor CCAAT enhancer binding protein beta (C/EBPβ) are expressed from a single intronless Cebpb...
6.
7.
Smink J, Leutz A
Gene
. 2012 Feb;
497(1):10-7.
PMID: 22306325
The transcription factor CCAAT/enhancer binding protein beta (C/EBPβ) plays a role in the differentiation of a large variety of cell types. C/EBPβ was initially described as an early inducer of...
8.
Smink J, Tunn P, Leutz A
J Mol Med (Berl)
. 2011 Nov;
90(1):25-30.
PMID: 22071989
Giant cell tumor (GCT) of bone is a benign type of tumor, but the presence of hyperactive multinucleated giant osteoclasts cause local osteolytic lesions, increasing morbidity in patients. To specifically...
9.
Courtial N, Smink J, Kuvardina O, Leutz A, Gothert J, Lausen J
FASEB J
. 2011 Oct;
26(2):523-32.
PMID: 21990371
The balance between bone-forming osteoblasts and bone-resorbing osteoclasts is crucial to bone homeostasis, an equilibrium that is disturbed in many bone diseases. The transcription factor Tal1 is involved in the...
10.
Wethmar K, Smink J, Leutz A
Bioessays
. 2010 Aug;
32(10):885-93.
PMID: 20726009
Conserved upstream open reading frames (uORFs) are found within many eukaryotic transcripts and are known to regulate protein translation. Evidence from genetic and bioinformatic studies implicates disturbed uORF-mediated translational control...