Jerzy Jan Jaroszewski
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Explore the profile of Jerzy Jan Jaroszewski including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Markowska P, Procajlo Z, Wolska J, Jaroszewski J, Ziolkowski H
Molecules
. 2021 Aug;
26(15).
PMID: 34361591
Each drug has pharmacokinetics that must be defined for the substance to be used in humans and animals. Currently, one of the basic analytical tools for pharmacokinetics studies is high-performance...
2.
Zygmuntowicz A, Markiewicz W, Grabowski T, Burmanczuk A, Vyniarska A, Jaroszewski J
PLoS One
. 2021 Jul;
16(7):e0252438.
PMID: 34270573
Quercetin is a polyphenolic flavonoid occurring in leaves, stems, flowers and fruits of many plants. In traditional Chinese medicine, it is used as a natural therapeutic agent with a broad...
3.
Markiewicz W, Bogacki M, Blitek M, Jaroszewski J
Acta Vet Scand
. 2016 Mar;
58:20.
PMID: 27004513
Background: Uterine contractile activity is very important for many reproductive functions including embryo transport, implantation, gestation and parturition. Abnormal contractility leads to implantation failure, spontaneous miscarriage, preterm birth and many...
4.
Grabowski T, Jaroszewski J, Gad S, Feder M
Int J Toxicol
. 2014 Nov;
33(6):490-7.
PMID: 25359732
The minimal inhibitory concentration (MIC) of an antimicrobial agent for a microbial population (MIC(50, obs) and MIC(90, obs)) is an interpolated value determined for antibacterial drugs by in vitro methods....
5.
Grabowski T, Raczynska-Pawelec A, Starosciak M, Jaroszewski J
Eur J Drug Metab Pharmacokinet
. 2014 Oct;
41(1):9-18.
PMID: 25312019
This study attempted to determine the area under the curve ([Formula: see text]), which corresponds to the sum of all elimination processes correlated with the total clearance value. The study...
6.
Maslanka T, Spodniewska A, Barski D, Jasiecka A, Zuska-Prot M, Ziolkowski H, et al.
Vet Immunol Immunopathol
. 2014 Jul;
160(3-4):192-200.
PMID: 25001909
A crucial event in the initiation of an immune response is the activation of T cells, which requires IL-2 binding to its high-affinity IL-2 receptor for optimal signaling. The IL-2...
7.
Grabowski T, Raczynska-Pawelec A, Starosciak M, Jaroszewski J
J Pharmacokinet Pharmacodyn
. 2014 Jun;
41(3):251-60.
PMID: 24952706
Key elements of pharmacokinetics (PK) studies include both, the number of sampling points (NSP) as well as the spacing between the sampling points (SSP). Optimization of the SSP is discussed...
8.
Grabowski T, Jaroszewski J, Piotrowski W, Sasinowska-Motyl M
Eur J Drug Metab Pharmacokinet
. 2013 Jun;
39(2):111-9.
PMID: 23780910
For many drugs administered per os, high variability in the concentration-time (C-T) values from first sampling to the phase of distribution may cause difficulty in pharmacokinetic analysis. Therefore, the aim...
9.
Maslanka T, Jaroszewski J
J Vet Sci
. 2013 May;
14(2):125-34.
PMID: 23628659
The purpose of this study was to evaluate the effect of meloxicam (MEL) on selected immune parameters of bovine CD25(high)CD4+, CD25(low)CD4+, and CD25-CD4+ cells. Peripheral blood mononuclear cells (PBMCs) collected...
10.
Maslanka T, Jaroszewski J
Vet Immunol Immunopathol
. 2012 Dec;
151(3-4):248-62.
PMID: 23266095
In view of the lack of data on the effect of meloxicam (non-steroidal anti-inflammatory drug) on bovine γδ T cells (WC1(+) cells) and very poorly recognized effects of dexamethasone (steroidal...