Jeronimo Auzmendi
Overview
Explore the profile of Jeronimo Auzmendi including associated specialties, affiliations and a list of published articles.
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20
Citations
222
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Recent Articles
1.
Zeballos L, Garcia-Peral C, Ledesma M, Auzmendi J, Lazarowski A, Lopez D
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076950
Epilepsy is a multifaceted neurological disorder characterized by recurrent seizures and associated with molecular and immune alterations in key brain regions. The GASH/Sal (Genetic Audiogenic Seizure Hamster, Salamanca), a genetic...
2.
Gomez C, Borda N, Moscovicz F, Fernandez F, Lazarowski A, Auzmendi J
Curr Pharm Des
. 2024 Jun;
30(28):2222-2228.
PMID: 38874045
Background: Cannabidiol (CBD) is the principal non-hallucinogenic compound of Cannabis plants with high clinical interest because CBD has been described as having anti-inflammatory, analgesic and anticonvulsant properties. CBD is considered...
3.
Akyuz E, Saleem Q, Sari C, Auzmendi J, Lazarowski A
Curr Med Chem
. 2023 Feb;
PMID: 36815654
Epilepsy is a chronic neurological degenerative disease with a high incidence, affecting all age groups. Refractory Epilepsy (RE) occurs in approximately 30-40% of cases with a higher risk of sudden...
4.
Czornyj L, Auzmendi J, Lazarowski A
Epilepsia Open
. 2021 Sep;
7 Suppl 1:S34-S46.
PMID: 34542938
The multidrug-resistance (MDR) phenotype is typically observed in patients with refractory epilepsy (RE) whose seizures are not controlled despite receiving several combinations of more than two antiseizure medications (ASMs) directed...
5.
Serral F, Castello F, Sosa E, Pardo A, Palumbo M, Modenutti C, et al.
Front Pharmacol
. 2021 Jun;
12:647060.
PMID: 34177572
Decades of successful use of antibiotics is currently challenged by the emergence of increasingly resistant bacterial strains. Novel drugs are urgently required but, in a scenario where private investment in...
6.
Gomez C, Lairion F, Repetto M, Ettcheto M, Merelli A, Lazarowski A, et al.
Pharmaceuticals (Basel)
. 2021 Apr;
14(3).
PMID: 33807975
Cannabidiol (CBD), a lipophilic cannabinoid compound without psychoactive effects, has emerged as adjuvant of anti-epileptic drugs (AEDs) in the treatment of refractory epilepsy (RE), decreasing the severity and/or frequency of...
7.
Akyuz E, Doganyigit Z, Eroglu E, Moscovicz F, Merelli A, Lazarowski A, et al.
Front Neurol
. 2021 Mar;
12:609236.
PMID: 33643194
Uncontrolled repetitive generalized tonic-clonic seizures (GTCS) are the main risk factor for sudden unexpected death in epilepsy (SUDEP). GTCS can be observed in models such as Pentylenetetrazole kindling (PTZ-K) or...
8.
Merelli A, Repetto M, Lazarowski A, Auzmendi J
J Alzheimers Dis
. 2020 Dec;
82(s1):S109-S126.
PMID: 33325385
The cerebral hypoxia-ischemia can induce a wide spectrum of biologic responses that include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and result in neurodegeneration. Several adaptive and survival endogenous mechanisms...
9.
Auzmendi J, Palestro P, Blachman A, Gavernet L, Merelli A, Talevi A, et al.
Front Behav Neurosci
. 2020 Apr;
14:32.
PMID: 32256321
Despite the constant development of new antiepileptic drugs (AEDs), more than 30% of patients develop refractory epilepsy (RE) characterized by a multidrug-resistant (MDR) phenotype. The "transporters hypothesis" indicates that the...
10.
Rocha L, Frias-Soria C, Ortiz J, Auzmendi J, Lazarowski A
Epilepsia Open
. 2020 Mar;
5(1):36-49.
PMID: 32140642
Cannabis has been considered as a therapeutic strategy to control intractable epilepsy. Several cannabis components, especially cannabidiol (CBD), induce antiseizure effects. However, additional information is necessary to identify the types...