Amalia Merelli
Overview
Explore the profile of Amalia Merelli including associated specialties, affiliations and a list of published articles.
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14
Citations
254
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Recent Articles
1.
Gomez C, Lairion F, Repetto M, Ettcheto M, Merelli A, Lazarowski A, et al.
Pharmaceuticals (Basel)
. 2021 Apr;
14(3).
PMID: 33807975
Cannabidiol (CBD), a lipophilic cannabinoid compound without psychoactive effects, has emerged as adjuvant of anti-epileptic drugs (AEDs) in the treatment of refractory epilepsy (RE), decreasing the severity and/or frequency of...
2.
Akyuz E, Doganyigit Z, Eroglu E, Moscovicz F, Merelli A, Lazarowski A, et al.
Front Neurol
. 2021 Mar;
12:609236.
PMID: 33643194
Uncontrolled repetitive generalized tonic-clonic seizures (GTCS) are the main risk factor for sudden unexpected death in epilepsy (SUDEP). GTCS can be observed in models such as Pentylenetetrazole kindling (PTZ-K) or...
3.
Merelli A, Repetto M, Lazarowski A, Auzmendi J
J Alzheimers Dis
. 2020 Dec;
82(s1):S109-S126.
PMID: 33325385
The cerebral hypoxia-ischemia can induce a wide spectrum of biologic responses that include depolarization, excitotoxicity, oxidative stress, inflammation, and apoptosis, and result in neurodegeneration. Several adaptive and survival endogenous mechanisms...
4.
Pastor R, Repetto M, Lairion F, Lazarowski A, Merelli A, Manfredi Carabetti Z, et al.
Nutrients
. 2020 Oct;
12(10).
PMID: 33076345
Metabolic Syndrome (MetS) is increasing worldwide regardless of culture, genetic, gender, and geographic differences. While multiple individual risk factors, such as obesity, hypertension, diabetes, and hyperlipidemia, can cause cardiovascular disease...
5.
Auzmendi J, Palestro P, Blachman A, Gavernet L, Merelli A, Talevi A, et al.
Front Behav Neurosci
. 2020 Apr;
14:32.
PMID: 32256321
Despite the constant development of new antiepileptic drugs (AEDs), more than 30% of patients develop refractory epilepsy (RE) characterized by a multidrug-resistant (MDR) phenotype. The "transporters hypothesis" indicates that the...
6.
Auzmendi J, Puchulu M, Rodriguez J, Balaszczuk A, Lazarowski A, Merelli A
Curr Pharm Des
. 2020 Feb;
26(12):1356-1364.
PMID: 32072891
The most important activity of erythropoietin (EPO) is the regulation of erythrocyte production by activation of the erythropoietin receptor (EPO-R), which triggers the activation of anti-apoptotic and proliferative responses of...
7.
Merelli A, Ramos A, Lazarowski A, Auzmendi J
Front Neurosci
. 2019 Aug;
13:750.
PMID: 31379495
Erythropoietin (EPO) is not only a hormone that promotes erythropoiesis but also has a neuroprotective effect on neurons attributed to its known anti-apoptotic action. Previously, our group has demonstrated that...
8.
Auzmendi J, Buchholz B, Salguero J, Canellas C, Kelly J, Men P, et al.
Pharmaceuticals (Basel)
. 2018 Feb;
11(1).
PMID: 29462915
Sudden unexpected death in epilepsy (SUDEP) is the major cause of death in those patients suffering from refractory epilepsy (RE), with a 24-fold higher risk relative to the normal population....
9.
Merelli A, Garcia Rodriguez J, Folch J, Regueiro M, Camins A, Lazarowski A
Curr Neuropharmacol
. 2018 Jan;
16(10):1484-1498.
PMID: 29318974
Neurodegeneration (NDG) is linked with the progressive loss of neural function with intellectual and/or motor impairment. Several diseases affecting older individuals, including Alzheimer's disease, Amyotrophic Lateral Sclerosis, Huntington's disease, Parkinson's...
10.
Merelli A, Czornyj L, Lazarowski A
Curr Pharm Des
. 2013 Mar;
19(38):6791-801.
PMID: 23530506
Neuronal damage secondary to brain injuries such as cerebral hypoxia, seizures as well as neurodegenerative process, may include pro-inflammatory changes. The activation of a common mechanism related to survival or...