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Jerome S Menet

Explore the profile of Jerome S Menet including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 1627
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Recent Articles
1.
Ogunlusi O, Ghosh A, Sarkar M, Carter K, Davuluri H, Chakraborty M, et al.
Crit Rev Oncol Hematol . 2025 Jan; 208:104632. PMID: 39864535
Physiological processes such as the sleep-wake cycle, metabolism, hormone secretion, neurotransmitter release, sensory capabilities, and a variety of behaviors, including sleep, are controlled by a circadian rhythm adapted to 24-hour...
2.
Nie X, Menet J
bioRxiv . 2024 May; PMID: 38712031
Cooperation between the circadian transcription factor (TF) CLOCK:BMAL1 and other TFs at -regulatory elements (CREs) is critical to daily rhythms of transcription. Yet, the modalities of this cooperation are unclear....
3.
Michael A, Stoos L, Crosby P, Eggers N, Nie X, Makasheva K, et al.
Nature . 2023 Jul; 619(7969):385-393. PMID: 37407816
The basic helix-loop-helix (bHLH) family of transcription factors recognizes DNA motifs known as E-boxes (CANNTG) and includes 108 members. Here we investigate how chromatinized E-boxes are engaged by two structurally...
4.
Sahasrabudhe A, Guy C, Greenwell B, Menet J
J Vis Exp . 2023 Jan; (190). PMID: 36591969
Rhythmic gene expression is a hallmark of the circadian rhythm and is essential for driving the rhythmicity of biological functions at the appropriate time of day. Studies over the last...
5.
Trott A, Greenwell B, Karhadkar T, Guerrero-Vargas N, Escobar C, Buijs R, et al.
BMC Biol . 2022 Mar; 20(1):58. PMID: 35236346
Background: Many epidemiological studies revealed that shift work is associated with an increased risk of a number of pathologies, including cardiovascular diseases. An experimental model of shift work in rats...
6.
Zhang Y, Iiams S, Menet J, Hardin P, Merlin C
Proc Natl Acad Sci U S A . 2022 Jan; 119(4). PMID: 35064085
Transcriptional repression drives feedback loops that are central to the generation of circadian (∼24-h) rhythms. In mammals, circadian repression of circadian locomotor output cycles kaput, and brain and muscle ARNT-like...
7.
Beytebiere J, Greenwell B, Sahasrabudhe A, Menet J
Transcription . 2019 Oct; 10(4-5):212-221. PMID: 31595813
Circadian clocks regulate the rhythmic expression of thousands of genes underlying the daily oscillations of biological functions. Here, we discuss recent findings showing that circadian clock rhythmic transcriptional outputs rely...
8.
Lugena A, Zhang Y, Menet J, Merlin C
PLoS Genet . 2019 Jul; 15(7):e1008265. PMID: 31335862
The Eastern North American monarch butterfly, Danaus plexippus, is famous for its spectacular seasonal long-distance migration. In recent years, it has also emerged as a novel system to study how...
9.
Greenwell B, Trott A, Beytebiere J, Pao S, Bosley A, Beach E, et al.
Cell Rep . 2019 Apr; 27(3):649-657.e5. PMID: 30995463
Every mammalian tissue exhibits daily rhythms in gene expression to control the activation of tissue-specific processes at the most appropriate time of the day. Much of this rhythmic expression is...
10.
Beytebiere J, Trott A, Greenwell B, Osborne C, Vitet H, Spence J, et al.
Genes Dev . 2019 Feb; 33(5-6):294-309. PMID: 30804225
The mammalian circadian clock relies on the transcription factor CLOCK:BMAL1 to coordinate the rhythmic expression of thousands of genes. Consistent with the various biological functions under clock control, rhythmic gene...