Jerome Egli
Overview
Explore the profile of Jerome Egli including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
23
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Recent Articles
1.
Egli J, Heiler S, Weber F, Steiner G, Schwandt T, Bray-French K, et al.
MAbs
. 2022 Nov;
14(1):2143009.
PMID: 36394299
ADA Anti-Drug Antibodies; BCR B Cell Receptor; BId Idiotype-specific B Cell; BiTE Bispecific T cell Engager; BMC Bone Marrow Chimeric Mice; BSA Bovine Serum Albumin; CDR Complementary Determining Region; CEA...
2.
Flisikowska T, Egli J, Flisikowski K, Stumbaum M, Kung E, Ebeling M, et al.
Nat Biomed Eng
. 2022 Sep;
6(11):1248-1256.
PMID: 36138193
The safety of most human recombinant proteins can be evaluated in transgenic mice tolerant to specific human proteins. However, owing to insufficient genetic diversity and to fundamental differences in immune...
3.
Egli J, Schlothauer T, Spick C, Seeber S, Singer T, Odermatt A, et al.
Pharm Res
. 2019 Feb;
36(3):47.
PMID: 30721414
Purpose: The Göttingen minipig is a relevant non-rodent species for regulatory toxicological studies. Yet, its use with therapeutic antibodies has been limited by the unknown binding properties of human immunoglobulins...
4.
Egli J, Schmucki R, Loos B, Reichl S, Grabole N, Roller A, et al.
Immunogenetics
. 2018 Dec;
71(2):123-136.
PMID: 30564855
Safety and efficacy of therapeutic antibodies are often dependent on their interaction with Fc receptors for IgG (FcγRs). The Göttingen minipig represents a valuable species for biomedical research but its...