Jeroen R Huyghe
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Explore the profile of Jeroen R Huyghe including associated specialties, affiliations and a list of published articles.
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88
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3513
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Recent Articles
1.
Chalitsios C, Markozannes G, Papagiannopoulos C, Aglago E, Berndt S, Buchanan D, et al.
Cancer Epidemiol Biomarkers Prev
. 2025 Feb;
PMID: 39898780
Background Waist circumference (WC) and its allometric counterpart, "a body shape index" (ABSI), are risk factors for colorectal cancer (CRC); however, it is uncertain whether associations with these body measurements...
2.
Thomas C, Takashima Y, Wesselink E, Ugai T, Steinfelder R, Buchanan D, et al.
Front Immunol
. 2025 Jan;
15:1505896.
PMID: 39763680
Background: Microsatellite instability-high (MSI-high) tumors comprise ~15% of sporadic colorectal cancers (CRC) and are associated with elevated T cell infiltration. However, the universality of this response across T cell subtypes...
3.
Wu E, Bieniosek M, Wu Z, Thakkar N, Charville G, Makky A, et al.
bioRxiv
. 2024 Nov;
PMID: 39605711
Hematoxylin and eosin (H&E) is a common and inexpensive histopathology assay. Though widely used and information-rich, it cannot directly inform about specific molecular markers, which require additional experiments to assess....
4.
McGee H, Bonner J, Egelston C, Fu Y, Flores O, Lindsey S, et al.
medRxiv
. 2024 Oct;
PMID: 39464256
The incidence of colorectal cancer (CRC) among individuals under age 50, or early-onset CRC (EOCRC), has been rising over the past few decades for unclear reasons, and the etiology of...
5.
Thomas C, Lin Y, Kim M, Kawaguchi E, Qu C, Um C, et al.
Epidemiology
. 2024 Sep;
36(1):126-138.
PMID: 39316822
Background: Colorectal cancer (CRC) is a common, fatal cancer. Identifying subgroups who may benefit more from intervention is of critical public health importance. Previous studies have assessed multiplicative interaction between...
6.
Aglago E, Qu C, Harlid S, Phipps A, Steinfelder R, Ogino S, et al.
Am J Clin Nutr
. 2024 Jul;
120(3):664-673.
PMID: 39025327
Background: Folate is involved in multiple genetic, epigenetic, and metabolic processes, and inadequate folate intake has been associated with an increased risk of cancer. Objective: We examined whether folate intake...
7.
Li Q, Song Q, Chen Z, Choi J, Moreno V, Ping J, et al.
medRxiv
. 2024 Jun;
PMID: 38853880
Identifying risk protein targets and their therapeutic drugs is crucial for effective cancer prevention. Here, we conduct integrative and fine-mapping analyses of large genome-wide association studies data for breast, colorectal,...
8.
Drew D, Kim A, Lin Y, Qu C, Morrison J, Lewinger J, et al.
Sci Adv
. 2024 May;
10(22):eadk3121.
PMID: 38809988
Regular, long-term aspirin use may act synergistically with genetic variants, particularly those in mechanistically relevant pathways, to confer a protective effect on colorectal cancer (CRC) risk. We leveraged pooled data...
9.
Papadimitriou N, Kim A, Kawaguchi E, Morrison J, Diez-Obrero V, Albanes D, et al.
EBioMedicine
. 2024 May;
104:105146.
PMID: 38749303
Background: Consumption of fibre, fruits and vegetables have been linked with lower colorectal cancer (CRC) risk. A genome-wide gene-environment (G × E) analysis was performed to test whether genetic variants...
10.
Chen Z, Guo X, Tao R, Huyghe J, Law P, Fernandez-Rozadilla C, et al.
Nat Commun
. 2024 Apr;
15(1):3557.
PMID: 38670944
Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We...