Jeroen Bussmann
Overview
Explore the profile of Jeroen Bussmann including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
40
Citations
1844
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bi D, Wilhelmy C, Unthan D, Keil I, Zhao B, Kolb B, et al.
Adv Healthc Mater
. 2024 Jun;
13(26):e2401252.
PMID: 38889433
Lipid nanoparticle (LNP) remains the most advanced platform for messenger RNA (mRNA) delivery. To date, mRNA LNPs synthesis is mostly performed by mixing lipids and mRNA with microfluidics. In this...
2.
Bi D, Van Hal A, Aschmann D, Shen M, Zhang H, Su L, et al.
Small
. 2024 Mar;
20(32):e2310781.
PMID: 38488770
Improving target versus off-target ratio in nanomedicine remains a major challenge for increasing drug bioavailability and reducing toxicity. Active targeting using ligands on nanoparticle surfaces is a key approach but...
3.
Verwilligen R, Mulder L, Araujo P, Carneiro M, Bussmann J, Hoekstra M, et al.
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 Mar;
1868(6):159308.
PMID: 36931457
Background And Aims: Scavenger receptor class B1 (SCARB1) - also known as the high-density lipoprotein (HDL) receptor - is a multi-ligand scavenger receptor that is primarily expressed in liver and...
4.
Bi D, Unthan D, Hu L, Bussmann J, Remaut K, Barz M, et al.
J Control Release
. 2023 Feb;
356:1-13.
PMID: 36803765
Messenger RNA (mRNA) is revolutionizing the future of therapeutics in a variety of diseases, including neurological disorders. Lipid formulations have shown to be an effective platform technology for mRNA delivery...
5.
Arias-Alpizar G, Papadopoulou P, Rios X, Pulagam K, Moradi M, Pattipeiluhu R, et al.
Adv Healthc Mater
. 2022 Dec;
12(10):e2202709.
PMID: 36565694
Plasma lipid transport and metabolism are essential to ensure correct cellular function throughout the body. Dynamically regulated in time and space, the well-characterized mechanisms underpinning plasma lipid transport and metabolism...
6.
He Y, Bi D, Plantinga J, Molema G, Bussmann J, Kamps J
Pharmaceutics
. 2022 Oct;
14(10).
PMID: 36297521
Low transfection efficiency in endothelial cells (EC) is still a bottleneck for the majority of siRNA-based vascular delivery approaches. In this work, we developed a lipid-based nanoparticle (LNP) formulation based...
7.
Giselbrecht J, Pinnapireddy S, Alioglu F, Sami H, Sedding D, Erdmann F, et al.
Small
. 2022 Mar;
18(18):e2107768.
PMID: 35355412
Formulations based on ionizable amino-lipids have been put into focus as nucleic acid delivery systems. Recently, the in vitro efficacy of the lipid formulation OH4:DOPE has been explored. However, in...
8.
Leonard E, Figueroa R, Bussmann J, Lawson N, Amigo J, Siekmann A
Development
. 2022 Mar;
149(7).
PMID: 35297968
Vascular networks comprise endothelial cells and mural cells, which include pericytes and smooth muscle cells. To elucidate the mechanisms controlling mural cell recruitment during development and tissue regeneration, we studied...
9.
Verwilligen R, Mulder L, Rodenburg F, Van Dijke A, Hoekstra M, Bussmann J, et al.
Atherosclerosis
. 2022 Mar;
346:18-25.
PMID: 35247629
Background And Aims: Scavenger receptors form a superfamily of membrane-bound receptors that bind and internalize different types of ligands, including pro-atherogenic oxidized low-density lipoproteins (oxLDLs). In vitro studies have indicated...
10.
Pattipeiluhu R, Arias-Alpizar G, Basha G, Chan K, Bussmann J, Sharp T, et al.
Adv Mater
. 2022 Feb;
34(16):e2201095.
PMID: 35218106
Lipid nanoparticles (LNPs) are the leading nonviral technologies for the delivery of exogenous RNA to target cells in vivo. As systemic delivery platforms, these technologies are exemplified by Onpattro, an...