Jeremy Schwartzentruber
Overview
Explore the profile of Jeremy Schwartzentruber including associated specialties, affiliations and a list of published articles.
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88
Citations
8178
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Recent Articles
1.
Buniello A, Suveges D, Cruz-Castillo C, Llinares M, Cornu H, Lopez I, et al.
Nucleic Acids Res
. 2024 Dec;
53(D1):D1467-D1475.
PMID: 39657122
The Open Targets Platform (https://platform.opentargets.org) is a unique, open-source, publicly-available knowledge base providing data and tooling for systematic drug target identification, annotation, and prioritisation. Since our last report, we have...
2.
West C, Karim M, Falaguera M, Speidel L, Green C, Logie L, et al.
Sci Data
. 2023 Sep;
10(1):655.
PMID: 37749083
Advancing age is the greatest risk factor for developing multiple age-related diseases. Therapeutic approaches targeting the underlying pathways of ageing, rather than individual diseases, may be an effective way to...
3.
Bettencourt C, Skene N, Bandres-Ciga S, Anderson E, Winchester L, Foote I, et al.
Alzheimers Dement
. 2023 Aug;
19(12):5905-5921.
PMID: 37606627
Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance our understanding of underlying mechanisms and pathways that can be targeted. We identified key remaining challenges: First, can...
4.
Kumasaka N, Rostom R, Huang N, Polanski K, Meyer K, Patel S, et al.
Nat Genet
. 2023 Jun;
55(6):1066-1075.
PMID: 37308670
Common genetic variants across individuals modulate the cellular response to pathogens and are implicated in diverse immune pathologies, yet how they dynamically alter the response upon infection is not well...
5.
Cooper S, Schwartzentruber J, Coomber E, Wu Q, Bassett A
Nucleic Acids Res
. 2023 May;
51(11):e64.
PMID: 37125635
Understanding the effects of genetic variation in gene regulatory elements is crucial to interpreting genome function. This is particularly pertinent for the hundreds of thousands of disease-associated variants identified by...
6.
Barrio-Hernandez I, Schwartzentruber J, Shrivastava A, Del-Toro N, Gonzalez A, Zhang Q, et al.
Nat Genet
. 2023 Feb;
55(3):389-398.
PMID: 36823319
Interacting proteins tend to have similar functions, influencing the same organismal traits. Interaction networks can be used to expand the list of candidate trait-associated genes from genome-wide association studies. Here,...
7.
Ochoa D, Hercules A, Carmona M, Suveges D, Baker J, Malangone C, et al.
Nucleic Acids Res
. 2022 Nov;
51(D1):D1353-D1359.
PMID: 36399499
The Open Targets Platform (https://platform.opentargets.org/) is an open source resource to systematically assist drug target identification and prioritisation using publicly available data. Since our last update, we have reimagined, redesigned,...
8.
Lynall M, Soskic B, Hayhurst J, Schwartzentruber J, Levey D, Pathak G, et al.
Nat Commun
. 2022 Oct;
13(1):6102.
PMID: 36243721
Multiple psychiatric disorders have been associated with abnormalities in both the innate and adaptive immune systems. The role of these abnormalities in pathogenesis, and whether they are driven by psychiatric...
9.
Zheng J, Zhang Y, Zhao H, Liu Y, Baird D, Karim M, et al.
EBioMedicine
. 2022 Jun;
81:104112.
PMID: 35772218
Background: Recent omic studies prioritised several drug targets associated with coronavirus disease 2019 (COVID-19) severity. However, little evidence was provided to systematically estimate the effect of drug targets on COVID-19...
10.
Huang L, Warman-Chardon J, Carter M, Friend K, Dudding T, Schwartzentruber J, et al.
Orphanet J Rare Dis
. 2022 Mar;
17(1):143.
PMID: 35351177
No abstract available.