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Adam M Fontebasso

Explore the profile of Adam M Fontebasso including associated specialties, affiliations and a list of published articles. Areas
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Citations 4239
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Recent Articles
1.
Fontebasso A, Rytlewski J, Blay J, Gladdy R, Wilky B
Surg Oncol Clin N Am . 2024 Feb; 33(2):387-408. PMID: 38401916
Soft tissue sarcomas (STSs), including gastrointestinal stromal tumors (GISTs), are mesenchymal neoplasms with heterogeneous clinical behavior and represent broad categories comprising multiple distinct biologic entities. Multidisciplinary management of these rare...
2.
Fontebasso A, Figueira S, Thavorn K, Glen P, Lampron J, Matar M
Trauma Surg Acute Care Open . 2021 Jan; 5(1):e000568. PMID: 33409372
Background: Trauma is a cause of significant morbidity and mortality globally, and patients with major trauma require specialized settings for multidisciplinary care. We sought to enumerate the variability of costs...
3.
Gilbert R, Fontebasso A, Park L, Tran A, Lampron J
J Trauma Acute Care Surg . 2020 Sep; 89(6):1225-1232. PMID: 32925577
Background: Hemothorax is a common sequelae following thoracic trauma and is associated with significant morbidity and mortality. Current guidelines recommend all traumatic hemothoraces be considered for drainage with tube thoracostomy...
4.
Morrissy A, Cavalli F, Remke M, Ramaswamy V, Shih D, Holgado B, et al.
Nat Genet . 2017 Apr; 49(5):780-788. PMID: 28394352
Spatial heterogeneity of transcriptional and genetic markers between physically isolated biopsies of a single tumor poses major barriers to the identification of biomarkers and the development of targeted therapies that...
5.
Fiset P, Fontebasso A, De Jay N, Gayden T, Nikbakht H, Majewski J, et al.
Pediatr Blood Cancer . 2016 Oct; 64(2):275-278. PMID: 27718322
A cerebellar pilocytic astrocytoma (PA) in a child recurred first with a PA histology and then with features of a ganglioglioma (GG). Molecular genetic analyses of the tumors confirmed a...
6.
Fontebasso A, Shirinian M, Khuong-Quang D, Bechet D, Gayden T, Kool M, et al.
Oncotarget . 2015 Sep; 6(31):31844-56. PMID: 26378811
Pilocytic astrocytoma (PA) is the most common brain tumor in children but is rare in adults, and hence poorly studied in this age group. We investigated 222 PA and report...
7.
Fontebasso A, Jabado N
Crit Rev Oncog . 2015 Sep; 20(3-4):271-99. PMID: 26349420
Primary malignant brain tumors remain a disproportionate cause of morbidity and mortality in humans. A number of studies exploring the cancer genome of brain tumors across ages using integrated genetics...
8.
Fontebasso A, Gayden T, Nikbakht H, Neirinck M, Papillon-Cavanagh S, Majewski J, et al.
Acta Neuropathol . 2014 Aug; 128(5):615-27. PMID: 25077668
A remarkably large number of "epigenetic regulators" have been recently identified to be altered in cancers and a rapidly expanding body of literature points to "epigenetic addiction" (an aberrant epigenetic...
9.
Fontebasso A, Papillon-Cavanagh S, Schwartzentruber J, Nikbakht H, Gerges N, Fiset P, et al.
Nat Genet . 2014 Apr; 46(5):462-6. PMID: 24705250
Pediatric midline high-grade astrocytomas (mHGAs) are incurable with few treatment targets identified. Most tumors harbor mutations encoding p.Lys27Met in histone H3 variants. In 40 treatment-naive mHGAs, 39 analyzed by whole-exome...
10.
Kleinman C, Gerges N, Papillon-Cavanagh S, Sin-Chan P, Pramatarova A, Quang D, et al.
Nat Genet . 2013 Dec; 46(1):39-44. PMID: 24316981
Embryonal tumors with multilayered rosettes (ETMRs) are rare, deadly pediatric brain tumors characterized by high-level amplification of the microRNA cluster C19MC. We performed integrated genetic and epigenetic analyses of 12...