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Jeremy Grenier

Explore the profile of Jeremy Grenier including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 137
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Recent Articles
1.
Denton K, Lei L, Grenier J, Rodionov V, Blackstone C, Li X
Stem Cells . 2013 Oct; 32(2):414-23. PMID: 24123785
Human neuronal models of hereditary spastic paraplegias (HSP) that recapitulate disease-specific axonal pathology hold the key to understanding why certain axons degenerate in patients and to developing therapies. SPG4, the...
2.
Amrein L, Shawi M, Grenier J, Aloyz R, Panasci L
Int J Cancer . 2012 Dec; 133(1):247-52. PMID: 23238639
BKM120, a pan class I PI3K inhibitor, was cytotoxic in the majority of primary B-chronic lymphocytic leukemia (CLL) lymphocytes, including samples from patients who have a high-risk for poor response...
3.
Davidson D, Grenier J, Martinez-Marignac V, Amrein L, Shawi M, Tokars M, et al.
Invest New Drugs . 2011 May; 30(4):1736-42. PMID: 21567185
The purpose of this study was to determine the degree to which the novel DNA-PKcs inhibitor, IC486241 (ICC), synergizes the cytotoxicity of DNA damaging agents in 3 genetically diverse breast...
4.
Davidson D, Coulombe Y, Martinez-Marignac V, Amrein L, Grenier J, Hodkinson K, et al.
Invest New Drugs . 2011 Jan; 30(3):1248-56. PMID: 21221710
This study sought to measure the degree of synergy induced by specific small molecule inhibitors of DNA-PK [NU7026 and IC486241 (ICC)], a major component of the non-homologous end-joining (NHEJ) pathway,...