Jeremy C Parker
Overview
Explore the profile of Jeremy C Parker including associated specialties, affiliations and a list of published articles.
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10
Citations
100
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Recent Articles
1.
Cuthbertson L, Lober U, Ish-Horowicz J, McBrien C, Churchward C, Parker J, et al.
Commun Biol
. 2024 Feb;
7(1):171.
PMID: 38347162
Microbial communities at the airway mucosal barrier are conserved and highly ordered, in likelihood reflecting co-evolution with human host factors. Freed of selection to digest nutrients, the airway microbiome underpins...
2.
Parker J, Douglas I, Bell J, Comer D, Bailie K, Skibinski G, et al.
PLoS One
. 2015 Jun;
10(6):e0129546.
PMID: 26057128
Rationale: Epithelial remodelling in asthma is characterised by goblet cell hyperplasia and mucus hypersecretion for which no therapies exist. Differentiated bronchial air-liquid interface cultures from asthmatic children display high goblet...
3.
Thavagnanam S, Parker J, McBrien M, Skibinski G, Shields M, Heaney L
PLoS One
. 2014 Jan;
9(1):e85802.
PMID: 24475053
Introduction: Differentiated paediatric epithelial cells can be used to study the role of epithelial cells in asthma. Nasal epithelial cells are easier to obtain and may act as a surrogate...
4.
Parker J, Thavagnanam S, Skibinski G, McBrien M, Heaney L, Shields M
Results Immunol
. 2013 Dec;
2:104-11.
PMID: 24371573
Background: IL-31 is a novel cytokine that has been implicated in allergic diseases such as atopic dermatitis and more recently asthma. While IL-31 has been well studied in skin conditions...
5.
Parker J, Thavagnanam S, Skibinski G, Lyons J, Bell J, Heaney L, et al.
PLoS One
. 2013 May;
8(5):e61023.
PMID: 23671562
Asthma is a chronic inflammatory disease characterised by airways remodelling. In mouse models IL-9 and IL-13 have been implicated in airways remodelling including mucus hypersecretion and goblet cell hyperplasia. Their...
6.
Thavagnanam S, Parker J, McBrien M, Skibinski G, Heaney L, Shields M
Pediatr Res
. 2010 Nov;
69(2):95-100.
PMID: 21076368
Goblet cell hyperplasia (GCH) and decreased ciliated cells are characteristic of asthma. We examined the effects of IL-13 (2 and 20 ng/mL) on in vitro mucociliary differentiation in pediatric bronchial...
7.
Parker J, Irwin N, Lavery K, Green B, Oharte F, Gault V, et al.
Biol Chem
. 2007 Jan;
388(2):221-6.
PMID: 17261085
Effects of chemical ablation of the GIP and GLP-1 receptors on metabolic aspects of obesity-diabetes were investigated using the stable receptor antagonists (Pro3)GIP and exendin(9-39)amide. Ob/ob mice received a daily...
8.
Irwin N, Green B, Parker J, Gault V, Oharte F, Flatt P
Regul Pept
. 2006 May;
135(1-2):45-53.
PMID: 16675042
Glucose-dependent insulinotropic polypeptide (GIP) is a key physiological insulin releasing peptide and potential antidiabetic agent. The present study was undertaken in an attempt to develop small molecular weight GIP agonist...
9.
Alana I, Parker J, Gault V, Flatt P, Oharte F, Paul G Malthouse J, et al.
J Biol Chem
. 2006 Apr;
281(24):16370-6.
PMID: 16621806
Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that stimulates the secretion of insulin after ingestion of food. GIP also promotes the synthesis of fatty acids in adipose tissue. Therefore,...
10.
Alana I, Hewage C, Paul G Malthouse J, Parker J, Gault V, Oharte F
Biochem Biophys Res Commun
. 2004 Nov;
325(1):281-6.
PMID: 15522230
Glucose-dependent insulinotropic polypeptide is an incretin hormone that stimulates insulin secretion and reduces postprandial glycaemic excursions. The glucose-dependent action of GIP on pancreatic beta-cells has attracted attention towards its exploitation...