Jeremy Burrows
Overview
Explore the profile of Jeremy Burrows including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
736
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Recent Articles
11.
Burrows J, Fidock D, Miller R, Rees S
Am J Trop Med Hyg
. 2019 Jul;
101(4):734-735.
PMID: 31264564
No abstract available.
12.
Schlott A, Mayclin S, Reers A, Coburn-Flynn O, Bell A, Green J, et al.
Cell Chem Biol
. 2019 May;
26(7):991-1000.e7.
PMID: 31080074
The attachment of myristate to the N-terminal glycine of certain proteins is largely a co-translational modification catalyzed by N-myristoyltransferase (NMT), and involved in protein membrane-localization. Pathogen NMT is a validated...
13.
Burrows J, Slater H, Macintyre F, Rees S, Thomas A, Okumu F, et al.
Malar J
. 2018 Dec;
17(1):462.
PMID: 30526594
Reaching the overall goal of eliminating malaria requires halting disease transmission. One approach to blocking transmission is to prevent passage of the parasite to a mosquito, by preventing formation or...
14.
Antonova-Koch Y, Meister S, Abraham M, Luth M, Ottilie S, Lukens A, et al.
Science
. 2018 Dec;
362(6419).
PMID: 30523084
To discover leads for next-generation chemoprotective antimalarial drugs, we tested more than 500,000 compounds for their ability to inhibit liver-stage development of luciferase-expressing spp. parasites (681 compounds showed a half-maximal...
15.
Nchinda A, Le Manach C, Paquet T, Gonzalez Cabrera D, Wicht K, Brunschwig C, et al.
J Med Chem
. 2018 Apr;
61(9):4213-4227.
PMID: 29665687
Optimization of a chemical series originating from whole-cell phenotypic screening against the human malaria parasite, Plasmodium falciparum, led to the identification of two promising 2,6-disubstituted imidazopyridine compounds, 43 and 74....
16.
Dechering K, Duerr H, Koolen K, van Gemert G, Bousema T, Burrows J, et al.
Sci Rep
. 2017 Dec;
7(1):17680.
PMID: 29247222
Eradication of malaria requires a novel type of drug that blocks transmission from the human to the mosquito host, but selection of such a drug is hampered by a lack...
17.
Sandoval E, Lafuente-Monasterio M, Almela M, Castaneda P, Jimenez Diaz M, Martinez-Martinez M, et al.
J Med Chem
. 2017 Nov;
60(23):9911.
PMID: 29164877
No abstract available.
18.
Sandoval E, Lafuente-Monasterio M, Almela M, Castaneda P, Jimenez Diaz M, Martinez-Martinez M, et al.
J Med Chem
. 2017 Aug;
60(16):6880-6896.
PMID: 28806082
Since the appearance of resistance to the current front-line antimalarial treatments, ACTs (artemisinin combination therapies), the discovery of novel chemical entities to treat the disease is recognized as a major...
19.
20.
Paquet T, Le Manach C, Gonzalez Cabrera D, Younis Y, Henrich P, Abraham T, et al.
Sci Transl Med
. 2017 Apr;
9(387).
PMID: 28446690
As part of the global effort toward malaria eradication, phenotypic whole-cell screening revealed the 2-aminopyridine class of small molecules as a good starting point to develop new antimalarial drugs. Stemming...