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Jeremiah S Joseph

Explore the profile of Jeremiah S Joseph including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 1418
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Recent Articles
1.
Goren M, Morizumi T, Menon I, Joseph J, Dittman J, Cherezov V, et al.
Nat Commun . 2014 Oct; 5:5115. PMID: 25296113
Opsin, the rhodopsin apoprotein, was recently shown to be an ATP-independent flippase (or scramblase) that equilibrates phospholipids across photoreceptor disc membranes in mammalian retina, a process required for disc homoeostasis....
2.
Gutierrez-de-Teran H, Massink A, Rodriguez D, Liu W, Han G, Joseph J, et al.
Structure . 2013 Nov; 21(12):2175-85. PMID: 24210756
The function of G protein-coupled receptors (GPCRs) can be modulated by a number of endogenous allosteric molecules. In this study, we used molecular dynamics, radioligand binding, and thermostability experiments to...
3.
Siu F, He M, de Graaf C, Han G, Yang D, Zhang Z, et al.
Nature . 2013 Jul; 499(7459):444-9. PMID: 23863937
Binding of the glucagon peptide to the glucagon receptor (GCGR) triggers the release of glucose from the liver during fasting; thus GCGR plays an important role in glucose homeostasis. Here...
4.
Seidel S, Dijkman P, Lea W, van den Bogaart G, Jerabek-Willemsen M, Lazic A, et al.
Methods . 2012 Dec; 59(3):301-15. PMID: 23270813
Microscale thermophoresis (MST) allows for quantitative analysis of protein interactions in free solution and with low sample consumption. The technique is based on thermophoresis, the directed motion of molecules in...
5.
Joseph J, Liu W, Kunken J, Weiss T, Tsuruta H, Cherezov V
Methods . 2011 Sep; 55(4):342-9. PMID: 21903166
The lipidic cubic phase (LCP) has repeatedly proven to serve as a successful membrane-mimetic matrix for a variety of difficult-to-crystallize membrane proteins. While monoolein has been the predominant lipid of...
6.
Elledge H, Kazmierczak P, Clark P, Joseph J, Kolatkar A, Kuhn P, et al.
Proc Natl Acad Sci U S A . 2010 May; 107(23):10708-12. PMID: 20498078
The cadherin superfamily encodes more than 100 receptors with diverse functions in tissue development and homeostasis. Classical cadherins mediate adhesion by binding interactions that depend on their N-terminal extracellular cadherin...
7.
Chandramouli S, Joseph J, Daudenarde S, Gatchalian J, Cornillez-Ty C, Kuhn P
J Virol . 2010 Jan; 84(6):3059-67. PMID: 20042502
With an estimated 40% of the world population at risk, dengue poses a significant threat to human health, especially in tropical and subtropical regions. Preventative and curative efforts, such as...
8.
Serrano P, Johnson M, Chatterjee A, Neuman B, Joseph J, Buchmeier M, et al.
J Virol . 2009 Oct; 83(24):12998-3008. PMID: 19828617
The nuclear magnetic resonance (NMR) structure of a globular domain of residues 1071 to 1178 within the previously annotated nucleic acid-binding region (NAB) of severe acute respiratory syndrome coronavirus nonstructural...
9.
Chatterjee A, Johnson M, Serrano P, Pedrini B, Joseph J, Neuman B, et al.
J Virol . 2008 Dec; 83(4):1823-36. PMID: 19052085
The nuclear magnetic resonance (NMR) structure of a central segment of the previously annotated severe acute respiratory syndrome (SARS)-unique domain (SUD-M, for "middle of the SARS-unique domain") in SARS coronavirus...
10.
Neuman B, Joseph J, Saikatendu K, Serrano P, Chatterjee A, Johnson M, et al.
J Virol . 2008 Mar; 82(11):5279-94. PMID: 18367524
Severe acute respiratory syndrome (SARS) coronavirus infection and growth are dependent on initiating signaling and enzyme actions upon viral entry into the host cell. Proteins packaged during virus assembly may...