Jeremiah D Degenhardt
Overview
Explore the profile of Jeremiah D Degenhardt including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
1988
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0
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Recent Articles
1.
Dettling D, Kwok E, Quach L, Datt A, Degenhardt J, Panchal A, et al.
J Immunother Cancer
. 2022 Jun;
10(6).
PMID: 35728872
Background: Despite clinical success with T cell engagers (TCEs) targeting hematological malignancies, achieving a safe and efficacious dose in patients with solid tumors remains challenging. Due to potency, low levels...
2.
Tausch E, Ljungstrom V, Agathangelidis A, Zapatka M, Scarfo L, Jebaraj B, et al.
Blood
. 2022 Apr;
139(22):3340-3344.
PMID: 35377939
No abstract available.
3.
Panchal A, Seto P, Wall R, Hillier B, Zhu Y, Krakow J, et al.
MAbs
. 2020 Jul;
12(1):1792130.
PMID: 32684124
Conditionally active COBRA™ (COnditional Bispecific Redirected Activation) T cell engagers are engineered to overcome the limitations of inherently active first-generation T cell engagers, which are unable to discern between tumor...
4.
Ma X, Kelley J, Eilertson K, Musharoff S, Degenhardt J, Martins A, et al.
PLoS One
. 2013 Nov;
8(10):e77175.
PMID: 24194868
To gain insights into evolutionary forces that have shaped the history of Bornean and Sumatran populations of orang-utans, we compare patterns of variation across more than 11 million single nucleotide...
5.
Kidd J, Gravel S, Byrnes J, Moreno-Estrada A, Musharoff S, Bryc K, et al.
Am J Hum Genet
. 2012 Oct;
91(4):660-71.
PMID: 23040495
Full sequencing of individual human genomes has greatly expanded our understanding of human genetic variation and population history. Here, we present a systematic analysis of 50 human genomes from 11...
6.
Seshagiri S, Stawiski E, Durinck S, Modrusan Z, Storm E, Conboy C, et al.
Nature
. 2012 Aug;
488(7413):660-4.
PMID: 22895193
Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary human colon tumours by applying...
7.
Boyko A, Quignon P, Li L, Schoenebeck J, Degenhardt J, Lohmueller K, et al.
PLoS Biol
. 2010 Aug;
8(8):e1000451.
PMID: 20711490
Domestic dogs exhibit tremendous phenotypic diversity, including a greater variation in body size than any other terrestrial mammal. Here, we generate a high density map of canine genetic variation by...
8.
Lohmueller K, Degenhardt J, Keinan A
Am J Hum Genet
. 2010 Jun;
86(6):978-80.
PMID: 20541048
No abstract available.
9.
vonHoldt B, Pollinger J, Lohmueller K, Han E, Parker H, Quignon P, et al.
Nature
. 2010 Mar;
464(7290):898-902.
PMID: 20237475
Advances in genome technology have facilitated a new understanding of the historical and genetic processes crucial to rapid phenotypic evolution under domestication. To understand the process of dog diversification better,...
10.
Andres A, Hubisz M, Indap A, Torgerson D, Degenhardt J, Boyko A, et al.
Mol Biol Evol
. 2009 Aug;
26(12):2755-64.
PMID: 19713326
Balancing selection is potentially an important biological force for maintaining advantageous genetic diversity in populations, including variation that is responsible for long-term adaptation to the environment. By serving as a...