Jeonghyun Ahn
Overview
Explore the profile of Jeonghyun Ahn including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
1614
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Ahn J, Xia T, Konno H, Konno K, Ruiz P, Barber G
Nat Commun
. 2014 Oct;
5:5166.
PMID: 25300616
Chronic stimulation of innate immune pathways by microbial agents or damaged tissue is known to promote inflammation-driven tumorigenesis by mechanisms that are not well understood. Here we demonstrate that mutagenic...
12.
Ahn J, Ruiz P, Barber G
J Immunol
. 2014 Sep;
193(9):4634-42.
PMID: 25261479
Inflammatory diseases such as Aicardi-Goutières syndrome and severe systemic lupus erythematosus are generally lethal disorders that have been traced to defects in the exonuclease TREX1 (DNase III). Mice lacking TREX1...
13.
Abe T, Harashima A, Xia T, Konno H, Konno K, Morales A, et al.
Mol Cell
. 2013 Mar;
50(1):5-15.
PMID: 23478444
How the cell recognizes cytosolic DNA including DNA-based microbes to trigger host-defense-related gene activation remains to be fully resolved. Here, we demonstrate that STING (stimulator of interferon genes), an endoplasmic...
14.
Ahn J, Gutman D, Saijo S, Barber G
Proc Natl Acad Sci U S A
. 2012 Nov;
109(47):19386-91.
PMID: 23132945
Inflammatory autoimmune diseases such as systemic lupus erythematosus (SLE) and polyarthritis are characterized by chronic cytokine overproduction, suggesting that the stimulation of host innate immune responses, speculatively by persistent infection...
15.
Ahn J, Woo H, Ko A, Khim M, Kim C, Park N, et al.
Cell Mol Life Sci
. 2012 May;
69(18):3147-58.
PMID: 22562582
Successful development of sequence-specific siRNA (small interfering RNA)-based drugs requires an siRNA design that functions consistently in different organisms. Utilizing the CAPSID program previously developed by our group, we here...
16.
Ahn J, Ko A, Jun E, Won M, Kim Y, Ju E, et al.
Antimicrob Agents Chemother
. 2012 Apr;
56(7):3516-23.
PMID: 22508300
Antiviral therapeutics are currently unavailable for treatment of coxsackievirus B3, which can cause life-threatening myocarditis. A modified small interfering RNA (siRNA) containing 5'-triphosphate, 3p-siRNA, was shown to induce RNA interference...
17.
Hwang J, Jun E, Seo I, Won M, Ahn J, Kim Y, et al.
Intervirology
. 2011 Nov;
55(5):333-41.
PMID: 22057046
To elucidate the detailed susceptibilities of leukocytes to clinically important non-polio enteroviruses (EVs), primary monocytes and various human leukocyte cell lines were infected with coxsackievirus A24 (CVA24), coxsackievirus B3 (CVB3),...
18.
Jun E, Won M, Ahn J, Ko A, Moon H, Tchah H, et al.
Invest Ophthalmol Vis Sci
. 2010 Aug;
52(1):58-63.
PMID: 20739472
Purpose: Acute hemorrhagic conjunctivitis (AHC), a highly contagious eye disease, is caused primarily by either enterovirus 70 (EV70) or coxsackievirus A24 (CVA24) infection. Yet methods to prevent or cure AHC...
19.
Lee H, Ahn J, Jun E, Yang S, Joo C, Kim Y, et al.
Biochem Biophys Res Commun
. 2009 May;
384(4):431-5.
PMID: 19422797
A major concern of antiviral therapy using small interfering RNAs (siRNAs) targeting RNA viral genome is high sequence diversity and mutation rate due to genetic instability. To overcome this problem,...
20.
Yoon S, Ha Y, Choi J, Ahn J, Lee H, Kim D
Autophagy
. 2009 Jan;
5(3):388-9.
PMID: 19158511
Autophagy is a process to engulf aberrant organelles or protein aggregates into double-membrane vesicles for lysosomal breakdown. Autophagy is a protective process against some intracellular bacteria and viruses; however, it...