Jeong Pil Han
Overview
Explore the profile of Jeong Pil Han including associated specialties, affiliations and a list of published articles.
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12
Citations
104
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Recent Articles
1.
Han J, Nam Y, Chung H, Lee H, Yeom S
Nano Lett
. 2024 Aug;
24(33):10380-10387.
PMID: 39120059
The advancement of effective nasal mucoadhesive delivery faces challenges due to rapid mucociliary clearance (MCC). Conventional studies have employed mucoadhesive materials, mainly forming spherical nanoparticles, but these offer limited adhesion...
2.
Lee J, Han J
Mol Diagn Ther
. 2024 Mar;
28(3):239-248.
PMID: 38538969
Hemophilia is a genetic disorder that is caused by mutations in coagulation factor VIII (hemophilia A) or IX (hemophilia B) genes resulting in blood clotting disorders. Despite advances in therapies,...
3.
Chung H, Lee G, Nam S, Lee J, Han J, Song S, et al.
Brain
. 2024 Jan;
147(6):2114-2127.
PMID: 38227798
Mutations in the Microrchidia CW-type zinc finger 2 (MORC2) GHKL ATPase module cause a broad range of neuropathies, such as Charcot-Marie-Tooth disease type 2Z; however, the aetiology and therapeutic strategy...
4.
Han J, Lee Y, Lee J, Chung H, Lee G, Nam Y, et al.
Mol Ther Nucleic Acids
. 2023 Nov;
34:102050.
PMID: 37916225
Gene therapy and rebalancing therapy have emerged as promising approaches for treating hemophilia A, but there are limitations, such as temporary efficacy due to individual differences. Genome editing for hemophilia...
5.
Lee J, Han J, Song D, Lee G, Choi B, Kim M, et al.
Mol Ther Nucleic Acids
. 2023 Apr;
32:161-172.
PMID: 37064777
Recent therapeutic strategies for hemophilia include long-term therapeutic gene expression using adeno-associated virus (AAV) and rebalancing therapy via the downregulation of anticoagulant pathways. However, these approaches have limitations in immune...
6.
Lee J, Oh H, Choi B, Lee H, Lee K, Kim U, et al.
Mol Ther Nucleic Acids
. 2022 Sep;
29:551-562.
PMID: 36090746
Recently, clinical trials of adeno-associated virus-mediated replacement therapy have suggested long-term therapeutic effects for several genetic diseases of the liver, including hemophilia. However, there remain concerns regarding decreased therapeutic effects...
7.
Han J, Kim M, Choi B, Lee J, Lee G, Jeong M, et al.
Sci Adv
. 2022 Jan;
8(3):eabj6901.
PMID: 35061543
Hemophilia is a hereditary disease that remains incurable. Although innovative treatments such as gene therapy or bispecific antibody therapy have been introduced, substantial unmet needs still exist with respect to...
8.
Lee G, Kwak G, Bae J, Han J, Nam S, Lee J, et al.
Dis Model Mech
. 2021 Oct;
14(10).
PMID: 34695197
The microrchidia (MORC)-family CW-type zinc finger 2 (MORC2) gene is related to DNA repair, adipogenesis and epigenetic silencing via the human silencing hub (HUSH) complex. MORC2 missense mutation is known...
9.
Han J, Song D, Lee J, Lee G, Yeom S
Biology (Basel)
. 2021 Aug;
10(8).
PMID: 34439937
Hemophilia A (HA) is an X-linked recessive blood coagulation disorder, and approximately 50% of severe HA patients are caused by intron 22 inversion (F8I22I). However, the F8I22I mouse model has...
10.
Han J, Lee J, Lee G, Koo O, Yeom S
Cells
. 2021 Apr;
10(5).
PMID: 33925396
Neuronal nitric oxide synthase (nNOS) has various roles as a neurotransmitter. However, studies to date have produced insufficient data to fully support the correlation between nNOS and bowel motility. This...