Jeong-Ah Kwak
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Explore the profile of Jeong-Ah Kwak including associated specialties, affiliations and a list of published articles.
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4
Citations
42
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Recent Articles
1.
Piperidylmethyloxychalcone improves immune-mediated acute liver failure via inhibiting TAK1 activity
Park S, Kwak J, Jung S, Ahn B, Cho W, Yun C, et al.
Exp Mol Med
. 2017 Nov;
49(11):e392.
PMID: 29147012
Mice deficient in the toll-like receptor (TLR) or the myeloid differentiation factor 88 (MyD88) are resistant to acute liver failure (ALF) with sudden death of hepatocytes. Chalcone derivatives from medicinal...
2.
Roh E, Lee H, Kwak J, Hong J, Nam S, Jung S, et al.
J Infect Dis
. 2011 Mar;
203(7):1012-20.
PMID: 21402551
Myeloid differentiation 2 (MD-2) recognizes endotoxin lipopolysaccharide (LPS), which is required for Toll-like receptor 4 (TLR4) activity. MD-2 represents a more attractive therapeutic target than TLR4 for intervention in severe...
3.
Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives
Kwak J, Kim Y, Park H, Jang J, Lee K, Yi W, et al.
Bioorg Med Chem Lett
. 2010 Jun;
20(15):4620-3.
PMID: 20579876
Chroman derivatives exhibited potent inhibitory activity of NF-kappaB. For SAR, the chroman scaffold was modified with an indoline moiety. A series of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives were synthesized to explore...
4.
Chung E, Roh E, Kwak J, Lee H, Lee S, Lee C, et al.
J Pharmacol Sci
. 2010 Apr;
112(4):405-14.
PMID: 20424383
alpha-Viniferin, an oligostilbene of trimeric resveratrol, has been reported to have anti-inflammatory potential in carrageenin-induced paw edema or adjuvant-induced arthritis in animal models. However, little is known about the molecular...