Jens S Andersen
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Explore the profile of Jens S Andersen including associated specialties, affiliations and a list of published articles.
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113
Citations
7875
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Recent Articles
11.
Goncalves A, Hasselbalch S, Joensen B, Patzke S, Martens P, Ohlsen S, et al.
Elife
. 2021 Jul;
10.
PMID: 34259627
CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in the gene cause retinal cone-rod dystrophy associated with hearing loss. However, the mechanism by which...
12.
Montes M, Lubas M, Arendrup F, Mentz B, Rohatgi N, Tumas S, et al.
Nat Commun
. 2021 Apr;
12(1):2459.
PMID: 33911076
Oncogene-induced senescence provides a barrier against malignant transformation. However, it can also promote cancer through the secretion of a plethora of factors released by senescent cells, called the senescence associated...
13.
Lokkegaard S, Elias D, Alves C, Bennetzen M, Laenkholm A, Bak M, et al.
NPJ Breast Cancer
. 2021 Jan;
7(1):2.
PMID: 33398005
Resistance to endocrine therapy in estrogen receptor-positive (ER) breast cancer is a major clinical problem with poorly understood mechanisms. There is an unmet need for prognostic and predictive biomarkers to...
14.
Veno M, Reschke C, Morris G, Connolly N, Su J, Yan Y, et al.
Proc Natl Acad Sci U S A
. 2020 Jun;
117(27):15977-15988.
PMID: 32581127
Temporal lobe epilepsy is the most common drug-resistant form of epilepsy in adults. The reorganization of neural networks and the gene expression landscape underlying pathophysiologic network behavior in brain structures...
15.
Bjorkman A, Johansen S, Lin L, Schertzer M, Kanellis D, Katsori A, et al.
Genes Dev
. 2020 Jun;
34(15-16):1065-1074.
PMID: 32561545
RTEL1 helicase is a component of DNA repair and telomere maintenance machineries. While RTEL1's role in DNA replication is emerging, how RTEL1 preserves genomic stability during replication remains elusive. Here...
16.
Danielsson F, Mahdessian D, Axelsson U, Sullivan D, Uhlen M, Andersen J, et al.
Proteomics
. 2020 Jun;
20(23):e1900361.
PMID: 32558245
After a century of research, the human centrosome continues to fascinate. Based on immunofluorescence and confocal microscopy, an extensive inventory of the protein components of the human centrosome, and the...
17.
Silla T, Schmid M, Dou Y, Garland W, Milek M, Imami K, et al.
Nucleic Acids Res
. 2020 Jan;
48(5):2518-2530.
PMID: 31950173
Recruitment of the human ribonucleolytic RNA exosome to nuclear polyadenylated (pA+) RNA is facilitated by the Poly(A) Tail eXosome Targeting (PAXT) connection. Besides its core dimer, formed by the exosome...
18.
Holdgaard S, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen J, et al.
Nat Commun
. 2019 Sep;
10(1):4176.
PMID: 31519908
The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome abnormalities are frequently observed in cancer, but little is known of their origin...
19.
Kuhns S, Seixas C, Pestana S, Tavares B, Nogueira R, Jacinto R, et al.
EMBO Rep
. 2019 Aug;
20(10):e47625.
PMID: 31432619
Rab and Arl guanine nucleotide-binding (G) proteins regulate trafficking pathways essential for the formation, function and composition of primary cilia, which are sensory devices associated with Sonic hedgehog (Shh) signalling...
20.
Bennetzen M, Kosar M, Bunkenborg J, Payne M, Bartkova J, Lindstrom M, et al.
Cell Cycle
. 2018 Sep;
17(17):2146-2163.
PMID: 30196736
Ionizing radiation (IR) causes DNA double-strand breaks (DSBs) and activates a versatile cellular response regulating DNA repair, cell-cycle progression, transcription, DNA replication and other processes. In recent years proteomics has...