Jens Marquardt
Overview
Explore the profile of Jens Marquardt including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
126
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0
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Recent Articles
1.
Schlicht K, Pape L, Rohmann N, Knappe C, Epe J, Geisler C, et al.
Gut Microbes
. 2025 Mar;
17(1):2474143.
PMID: 40045464
The interplay between bile acids (BAs) and metabolic diseases has gained importance in recent years, with a variety of studies investigating their relationship with diverging results. Therefore, in the present...
2.
Nording H, Baron L, Sauter M, Lubken A, Rawish E, Szepanowski R, et al.
Blood Adv
. 2023 May;
7(21):6411-6427.
PMID: 37257194
In ischemic tissue, platelets can modulate angiogenesis. The specific factors influencing this function, however, are poorly understood. Here, we characterized the complement anaphylatoxin C5a-mediated activation of C5a receptor 1 (C5aR1)...
3.
Pruessmann J, Langan E, Rupp J, Marquardt J, Terheyden P, Zillikens D, et al.
J Dermatol
. 2022 Jun;
49(10):1049-1051.
PMID: 35726741
Intravenous immunoglobulin (IVIg) contains pooled immunoglobulins from the plasma of healthy blood donors. All plasma samples are tested for HIV, hepatitis viruses (A, B, and C), and parvovirus B19. As...
4.
Moehler M, Michel M, Stein A, Trojan J, Marquardt J, Tintelnot J, et al.
Future Oncol
. 2021 May;
17(25):3309-3319.
PMID: 33993741
To determine a recommended Phase II dose of the oral fluoropyrimidine trifluridine/tipiracil (FTD/TPI) combined with the multi-kinase inhibitor regorafenib (REG) in refractory metastatic colorectal cancer patients. A conventional 3 + ...
5.
Marquard S, Thomann S, Weiler S, Bissinger M, Lutz T, Sticht C, et al.
Cell Commun Signal
. 2020 Oct;
18(1):166.
PMID: 33097058
Background: Overexpression and nuclear enrichment of the oncogene yes-associated protein (YAP) cause tumor initiation and support tumor progression in human hepatocellular carcinoma (HCC) via cell autonomous mechanisms. However, how YAP...
6.
Fako V, Martin S, Pomyen Y, Budhu A, Chaisaingmongkol J, Franck S, et al.
Int J Biol Sci
. 2019 Nov;
15(12):2654-2663.
PMID: 31754337
Transarterial chemoembolization (TACE) is a commonly used treatment modality in hepatocellular carcinoma (HCC). The ability to identify patients who will respond to TACE represents an important clinical need, and tumor...
7.
Wei T, Weiler S, Toth M, Sticht C, Lutz T, Thomann S, et al.
Oncogene
. 2019 Apr;
38(27):5541-5550.
PMID: 30936457
The oncogene yes-associated protein (YAP) is a key modifier of liver homeostasis and regulates mitosis in hepatocytes as well as in malignantly transformed cells. However, the question of how YAP...
8.
Kirstein M, Voigtlander T, Schweitzer N, Hinrichs J, Marquardt J, Worns M, et al.
United European Gastroenterol J
. 2018 Mar;
6(2):238-246.
PMID: 29511553
Background: Sorafenib is the recommended treatment for advanced hepatocellular carcinoma (HCC), but transarterial chemoembolization (TACE) is performed in individual cases with limited extrahepatic spread. The aim of this study was...
9.
Wan S, Meyer A, Weiler S, Rupp C, Toth M, Sticht C, et al.
Hepatology
. 2017 Nov;
67(5):1842-1856.
PMID: 29152770
Conclusion: Perturbation of hepatocellular polarity due to overexpression and cytoplasmic enrichment of Scrib supports tumor initiation and HCC cell dissemination through specific molecular mechanisms. Biomarker signatures identified in this study...
10.
Maass T, Marquardt J, Lee J, Krupp M, Scholz-Kreisel P, Mogler C, et al.
Oncotarget
. 2015 Apr;
7(20):28903-13.
PMID: 25826080
Dkk2 a antagonist of the Wnt/β-catenin-signaling pathway was shown to be silenced in diverse cancers. More recent data indicate that Dkk family members may also possess functions independent of Wnt-signaling...