Jens Kockskamper
Overview
Explore the profile of Jens Kockskamper including associated specialties, affiliations and a list of published articles.
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52
Citations
1000
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Recent Articles
1.
Konigstein D, Fender H, Plackic J, Kisko T, Wohr M, Kockskamper J
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769475
encodes the α1c subunit of the L-type Ca channel, Cav1.2. Ventricular myocytes from haploinsufficient () rats exhibited reduced expression of Cav1.2 but an apparently normal sarcolemmal Ca influx with an...
2.
Rinne A, Kockskamper J, Pluteanu F
Front Cardiovasc Med
. 2024 Aug;
11:1461311.
PMID: 39087076
No abstract available.
3.
Hermes J, Borisova V, Kockskamper J
Cells
. 2023 Dec;
12(23).
PMID: 38067118
Store-operated calcium entry (SOCE) in cardiomyocytes may be involved in cardiac remodeling, but the underlying mechanisms remain elusive. We hypothesized that SOCE may increase nuclear calcium, which alters gene expression...
4.
Fender H, Walter K, Kiper A, Plackic J, Kisko T, Braun M, et al.
Int J Mol Sci
. 2023 Jun;
24(12).
PMID: 37372947
encodes the pore-forming α1C subunit of the L-type Ca channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient rats represent a recently developed...
5.
Kockskamper J, Pluteanu F
Cells
. 2022 Oct;
11(19).
PMID: 36231118
Arterial hypertension affects ≈ 1 billion people worldwide. It is associated with increased morbidity and mortality and responsible for millions of deaths each year. Hypertension mediates damage of target organs...
6.
Euler G, Kockskamper J, Schulz R, Parahuleva M
Int J Mol Sci
. 2021 Apr;
22(8).
PMID: 33923401
Heart failure (HF) and atrial fibrillation (AF) are two major life-threatening diseases worldwide. Causes and mechanisms are incompletely understood, yet current therapies are unable to stop disease progression. In this...
7.
Niemann B, Li L, Simm A, Molenda N, Kockskamper J, Boening A, et al.
Sci Rep
. 2021 Jan;
11(1):1931.
PMID: 33479375
Increased activation of sympathetic nervous system contributes to congestive heart failure (CHF) progression, and inhibition of sympathetic overactivation by beta-blockers is successful in CHF patients. Similarly, caloric restriction (CR) reduces...
8.
Parahuleva M, Kockskamper J, Heger J, Grimm W, Scherer A, Buhler S, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33265909
Background: Cardiac-specific JDP2 overexpression provokes ventricular dysfunction and atrial dilatation in mice. We performed in vivo studies on JDP2-overexpressing mice to investigate the impact of JDP2 on the predisposition to...
9.
Kiess T, Kockskamper J
Front Physiol
. 2019 Feb;
10:56.
PMID: 30787882
In cardiomyocytes, nuclear calcium is involved in regulation of transcription and, thus, remodeling. The cellular mechanisms regulating nuclear calcium, however, remain elusive. Therefore, the aim of this study was to...
10.
Thomas D, Christ T, Fabritz L, Goette A, Hammwohner M, Heijman J, et al.
Clin Res Cardiol
. 2018 Oct;
108(6):577-599.
PMID: 30306295
Cardiac arrhythmias remain a common challenge and are associated with significant morbidity and mortality. Effective and safe rhythm control strategies are a primary, yet unmet need in everyday clinical practice....