Jens C Thies
Overview
Explore the profile of Jens C Thies including associated specialties, affiliations and a list of published articles.
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11
Citations
83
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Recent Articles
1.
Lopez Barreiro D, Houben K, Schouten O, Koenderink G, Thies J, Sagt C
ACS Appl Mater Interfaces
. 2024 Dec;
17(1):650-662.
PMID: 39681513
The biofabrication of recombinant structural proteins with a range of mechanical or structural features usually relies on the generation of protein libraries displaying variations in terms of amino acid composition,...
2.
van Hugten P, Jeuken R, Asik E, Oevering H, Welting T, van Donkelaar C, et al.
J Biomed Mater Res A
. 2024 Mar;
112(9):1424-1435.
PMID: 38465895
Currently available focal knee resurfacing implants (FKRIs) are fully or partially composed of metals, which show a large disparity in elastic modulus relative to bone and cartilage tissue. Although titanium...
3.
Lopez Barreiro D, Folch-Fortuny A, Muntz I, Thies J, Sagt C, Koenderink G
Biomacromolecules
. 2022 Dec;
24(1):489-501.
PMID: 36516874
The biofabrication of structural proteins with controllable properties via amino acid sequence design is interesting for biomedicine and biotechnology, yet a complete framework that connects amino acid sequence to material...
4.
Asik E, Damen A, van Hugten P, Roth A, Thies J, Emans P, et al.
J Orthop Res
. 2022 Feb;
40(10):2402-2413.
PMID: 35128715
The clinical success of osteochondral implants depends significantly on their surface properties. In vivo, an implant may roughen over time which can decrease its performance. The present study investigates whether...
5.
Wiersema T, Tellegen A, Beukers M, van Stralen M, Wouters E, van de Vooren M, et al.
Pharmaceutics
. 2021 Aug;
13(8).
PMID: 34452138
Back pain affects millions globally and in 40% of the cases is attributed to intervertebral disc degeneration. Oral analgesics are associated with adverse systemic side-effects and insufficient pain relief. Local...
6.
Lopez Barreiro D, Minten I, Thies J, Sagt C
ACS Biomater Sci Eng
. 2021 Jul;
9(7):3796-3809.
PMID: 34251181
Elastin is a structural protein with outstanding mechanical properties (e.g., elasticity and resilience) and biologically relevant functions (e.g., triggering responses like cell adhesion or chemotaxis). It is formed from its...
7.
Jeuken R, Roth A, Peters M, Welting T, van Rhijn L, Koenen J, et al.
J Biomed Mater Res B Appl Biomater
. 2020 Jul;
108(8):3370-3382.
PMID: 32614486
Focal knee resurfacing implants (FKRIs) are intended to treat cartilage defects in middle-aged patients. Most FKRIs are metal-based, which hampers follow-up of the joint using magnetic resonance imaging and potentially...
8.
Jeuken R, Roth A, Peters R, van Donkelaar C, Thies J, van Rhijn L, et al.
Polymers (Basel)
. 2019 Apr;
8(6).
PMID: 30979313
Cartilage defects in the knee are often seen in young and active patients. There is a need for effective joint preserving treatments in patients suffering from cartilage defects, as untreated...
9.
van Eldijk M, Smits F, Thies J, Mecinovic J, van Hest J
J Biotechnol
. 2014 Mar;
179:32-41.
PMID: 24667538
Antibodies, such as IgGs, are widely applied as detection probes, purification ligands and targeting moieties in research and medicine. Protein A from Staphylococcus aureus is capable of selectively binding to...
10.
Carette N, Engelkamp H, Akpa E, Pierre S, Cameron N, Christianen P, et al.
Nat Nanotechnol
. 2008 Jul;
2(4):226-9.
PMID: 18654267
Virus particles are probably the most precisely defined nanometre-sized objects that can be formed by protein self-assembly. Although their natural function is the storage and transport of genetic material, they...