Jens-Albert Broscheit
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Explore the profile of Jens-Albert Broscheit including associated specialties, affiliations and a list of published articles.
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75
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Recent Articles
1.
Chen S, Lotz C, Roewer N, Broscheit J
Eur J Med Res
. 2018 Feb;
23(1):10.
PMID: 29458412
Volatile anesthetic-induced preconditioning (APC) has shown to have cardiac and cerebral protective properties in both pre-clinical models and clinical trials. Interestingly, accumulating evidences demonstrate that, except from some specific characters,...
2.
Shityakov S, Roewer N, Forster C, Broscheit J
Comput Biol Chem
. 2017 Sep;
70:191-197.
PMID: 28917201
All-atom molecular dynamics (MD) simulations are presented on general anesthetic propofol bound to human serum albumin (HSA) due to the drug pharmacokinetics and pharmacodynamics in the circulatory system. We implemented...
3.
Shityakov S, Roewer N, Forster C, Broscheit J
Nanoscale Res Lett
. 2017 Jul;
12(1):439.
PMID: 28683535
The purpose of this study was to develop and implement an in silico model of indigoid-based single-electron transistor (SET) nanodevices, which consist of indigoid molecules from natural dye weakly coupled...
4.
Sauer R, Rittner H, Roewer N, Sohajda T, Shityakov S, Brack A, et al.
Anesth Analg
. 2016 Dec;
124(2):675-685.
PMID: 27930390
Background: Inhibitors of cyclooxygenase, which block the formation of prostaglandin (PG) E2, are the standard treatment of inflammatory pain. These drugs, however, have serious gastrointestinal, renal, and cardiovascular side effects...
5.
Shityakov S, Ekhteiari Salmas R, Durdagi S, Salvador E, Papai K, Yanez-Gascon M, et al.
J Chem Inf Model
. 2016 Sep;
56(10):1914-1922.
PMID: 27589557
In this study, we investigated the ability of the general anesthetic propofol (PR) to form inclusion complexes with modified β-cyclodextrins, including sulfobutylether-β-cyclodextrin (SBEβCD) and hydroxypropyl-β-cyclodextrin (HPβCD). The PR/SBEβCD and PR/HPβCD...
6.
Shityakov S, Puskas I, Papai K, Salvador E, Roewer N, Forster C, et al.
Molecules
. 2015 Jun;
20(6):10264-79.
PMID: 26046323
The objective of the present investigation was to study the ability of sulfobutylether-β-cyclodextrin (SBEβCD) to form an inclusion complex with sevoflurane (SEV), a volatile anesthetic with poor water solubility. The...
7.
Shityakov S, Sohajda T, Puskas I, Roewer N, Forster C, Broscheit J
Molecules
. 2014 Oct;
19(10):16861-76.
PMID: 25338177
We investigated the ionization profiles for open-ring (OR) and closed-ring (CR) forms of midazolam and drug-binding modes with heptakis-(2,3,6-tri-O-methyl)-β-cyclodextrin (trimethyl-β-cyclodextrin; TRIMEB) using molecular modeling techniques and quantum mechanics methods. The...
8.
Bleise S, Einhaus F, Pfeiffer K, Broscheit J, Greim C
Anasthesiol Intensivmed Notfallmed Schmerzther
. 2011 Dec;
46(11-12):750-4.
PMID: 22147612
Understanding the principles of wave physics paves the way for appropriate utilization and interpretation of sonography. In module 1 of the course series "Anesthesia Focused Sonography", the course participants will...
9.
Broscheit J, Weidemann F, Strotmann J, Steendijk P, Eberbach N, Karle H, et al.
J Cardiothorac Vasc Anesth
. 2008 Oct;
22(6):823-31.
PMID: 18834794
Objective: Myocardial contractility can be described by the relationship between blood-flow velocity in the carotid artery and the left ventricular cross-sectional area. The authors investigated whether critical myocardial ischemia influences...
10.
Broscheit J, Weidemann F, Strotmann J, Steendijk P, Karle H, Roewer N, et al.
J Cardiothorac Vasc Anesth
. 2006 Jun;
20(3):340-6.
PMID: 16750733
Objective: In this study, the relationship V(f)AR, which was obtained from carotid blood-flow velocity (V(f)) and the cross-sectional area (A) of the left ventricle, was used to assess changes in...