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Jenny Zhaoying Xiang

Explore the profile of Jenny Zhaoying Xiang including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 425
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Recent Articles
1.
Ohara K, Al Assaad M, McNulty S, Alnajar H, Sboner A, Wilkes D, et al.
J Neuropathol Exp Neurol . 2024 Sep; 84(3):269-271. PMID: 39340835
No abstract available.
2.
Zeng H, Guo M, Zhou T, Tan L, Chong C, Zhang T, et al.
Cell Stem Cell . 2024 Sep; 31(10):1543-1547. PMID: 39321799
No abstract available.
3.
Yang N, Wang Y, Dai P, Li T, Zierhut C, Tan A, et al.
Nat Commun . 2023 May; 14(1):2898. PMID: 37217469
The DNA sensor cyclic GMP-AMP synthase (cGAS) is critical in host antiviral immunity. Vaccinia virus (VACV) is a large cytoplasmic DNA virus that belongs to the poxvirus family. How vaccinia...
4.
Yang N, Wang Y, Liu S, Tariq S, Luna J, Mazo G, et al.
J Exp Med . 2023 May; 220(8). PMID: 37145142
Effective depletion of immune suppressive regulatory T cells (Tregs) in the tumor microenvironment without triggering systemic autoimmunity is an important strategy for cancer immunotherapy. Modified vaccinia virus Ankara (MVA) is...
5.
Gomez-Salinero J, Itkin T, Houghton S, Badwe C, Lin Y, Kalna V, et al.
Nat Cardiovasc Res . 2023 Jan; 1:882-899. PMID: 36713285
Current dogma dictates that during adulthood, endothelial cells (ECs) are locked in an immutable stable homeostatic state. By contrast, herein we show that maintenance of EC fate and function are...
6.
Jessurun J, Orr C, McNulty S, Hagen C, Alnajar H, Wilkes D, et al.
Am J Surg Pathol . 2022 Aug; 47(1):65-73. PMID: 35968961
GLI1 encodes a transcription factor that targets cell cycle regulators affecting stem cell proliferation. GLI1 gene fusions were initially described in pericytomas with a t[7;12] translocation and more recently in...
7.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, et al.
iScience . 2022 Apr; 25(4):104153. PMID: 35434558
The sinoatrial node (SAN) is the primary pacemaker of the heart. The human SAN is poorly understood due to limited primary tissue access and limitations in robust derivation methods. We...
8.
Gomez-Salinero J, Izzo F, Lin Y, Houghton S, Itkin T, Geng F, et al.
Cell Stem Cell . 2022 Apr; 29(4):593-609.e7. PMID: 35364013
The liver vascular network is patterned by sinusoidal and hepatocyte co-zonation. How intra-liver vessels acquire their hierarchical specialized functions is unknown. We study heterogeneity of hepatic vascular cells during mouse...
9.
Beg S, Bareja R, Ohara K, Eng K, Wilkes D, Pisapia D, et al.
Transl Oncol . 2020 Nov; 14(1):100944. PMID: 33190043
Background: Frequency of clinically relevant mutations in solid tumors by targeted and whole-exome sequencing is ∼30%. Transcriptome analysis complements detection of actionable gene fusions in advanced cancer patients. Goal of...
10.
Sailer V, Eng K, Zhang T, Bareja R, Pisapia D, Sigaras A, et al.
JCO Precis Oncol . 2019 Oct; 3. PMID: 31592503
Purpose: We developed a precision medicine program for patients with advanced cancer using integrative whole-exome sequencing and transcriptome analysis. Patients And Methods: Five hundred fifteen patients with locally advanced/metastatic solid...