Jennifer Spooner
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Explore the profile of Jennifer Spooner including associated specialties, affiliations and a list of published articles.
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6
Citations
73
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Recent Articles
1.
Lanier A, Schemera B, Rynders P, Kendall T, Petrofski M, Spooner J, et al.
J Am Assoc Lab Anim Sci
. 2025 Mar;
64(1):89-97.
PMID: 40035216
The laboratory opossum, Monodelphis domestica, serves as a critical marsupial model in biomedical research. Proper feeding approaches are essential for promoting animal growth and wellbeing. In this study, we systematically...
2.
Cao W, Horzmann K, Schemera B, Petrofski M, Kendall T, Spooner J, et al.
Front Genet
. 2023 Mar;
14:1073461.
PMID: 36873954
Perfluoroalkyl and poly-fluoroalkyl substances (PFASs) are widely used in industrial and consumer products. Due to their environmental persistence and bioaccumulation, PFASs can be found in the blood of humans and...
3.
Chodorge M, Celeste A, Grimsby J, Konkar A, Davidsson P, Fairman D, et al.
Sci Rep
. 2018 Dec;
8(1):17545.
PMID: 30510163
Type 2 diabetes (T2D) is a complex and progressive disease requiring polypharmacy to manage hyperglycaemia and cardiovascular risk factors. However, most patients do not achieve combined treatment goals. To address...
4.
Nimrod G, Fischman S, Austin M, Herman A, Keyes F, Leiderman O, et al.
Cell Rep
. 2018 Nov;
25(8):2121-2131.e5.
PMID: 30463010
The ultimate goal of protein design is to introduce new biological activity. We propose a computational approach for designing functional antibodies by focusing on functional epitopes, integrating large-scale statistical analysis...
5.
Popovic B, Gibson S, Senussi T, Carmen S, Kidd S, Slidel T, et al.
Protein Eng Des Sel
. 2017 Jan;
30(4):303-311.
PMID: 28130326
High levels of protein expression are key to the successful development and manufacture of a therapeutic antibody. Here, we describe two related antibodies, Ab001 and Ab008, where Ab001 shows a...
6.
Buchanan A, Newton P, Pehrsson S, Inghardt T, Antonsson T, Svensson P, et al.
Blood
. 2015 Mar;
125(22):3484-90.
PMID: 25788700
Ticagrelor is a direct-acting reversibly binding P2Y12 antagonist and is widely used as an antiplatelet therapy for the prevention of cardiovascular events in acute coronary syndrome patients. However, antiplatelet therapy...
7.
Spooner J, Keen J, Nayyar K, Birkett N, Bond N, Bannister D, et al.
Biotechnol Bioeng
. 2015 Jan;
112(7):1472-7.
PMID: 25619171
Fabs are an important class of antibody fragment as both research reagents and therapeutic agents. There are a plethora of methods described for their recombinant expression and purification. However, these...