Jennifer N Dines
Overview
Explore the profile of Jennifer N Dines including associated specialties, affiliations and a list of published articles.
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17
Citations
505
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Recent Articles
1.
Nolan S, Vignali M, Klinger M, Dines J, Kaplan I, Svejnoha E, et al.
Front Immunol
. 2025 Mar;
16:1488851.
PMID: 40034696
We describe the establishment and current content of the ImmuneCODE™ database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects exposed to or infected with...
2.
Snyder T, Gittelman R, Klinger M, May D, Osborne E, Taniguchi R, et al.
Front Immunol
. 2025 Jan;
15():1488860.
PMID: 39840037
Introduction: T cells are involved in the early identification and clearance of viral infections and also support the development of antibodies by B cells. This central role for T cells...
3.
Gebbia M, Zimmerman D, Jiang R, Nguyen M, Weile J, Li R, et al.
Am J Hum Genet
. 2024 Dec;
111(12):2675-2692.
PMID: 39642869
The tumor suppressor CHEK2 encodes the serine/threonine protein kinase CHK2 which, upon DNA damage, is important for pausing the cell cycle, initiating DNA repair, and inducing apoptosis. CHK2 phosphorylation of...
4.
Keitany G, Rubin B, Garrett M, Musa A, Tracy J, Liang Y, et al.
Cell Chem Biol
. 2023 Aug;
30(11):1377-1389.e8.
PMID: 37586370
TruAB Discovery is an approach that integrates cellular immunology, high-throughput immunosequencing, bioinformatics, and computational biology in order to discover naturally occurring human antibodies for prophylactic or therapeutic use. We adapted...
5.
Dalai S, Dines J, Snyder T, Gittelman R, Eerkes T, Vaney P, et al.
Clin Infect Dis
. 2022 May;
75(12):2079-2087.
PMID: 35521791
Background: While diagnostic, therapeutic, and vaccine development in the coronavirus disease 2019 (COVID-19) pandemic has proceeded at unprecedented speed, critical gaps in our understanding of the immune response to severe...
6.
Fayer S, Horton C, Dines J, Rubin A, Richardson M, McGoldrick K, et al.
Am J Hum Genet
. 2021 Nov;
108(12):2248-2258.
PMID: 34793697
Clinical interpretation of missense variants is challenging because the majority identified by genetic testing are rare and their functional effects are unknown. Consequently, most variants are of uncertain significance and...
7.
Dines J, Eckel A, Cheng E, Lockwood C
J Appl Lab Med
. 2021 Feb;
2(5):784-796.
PMID: 33636864
Background: Testing to determine the health of a fetus has undergone multiple iterations since the widespread adoption of amniocentesis in the 1970s, including several combinations of ultrasound and/or maternal serum...
8.
Snyder T, Gittelman R, Klinger M, May D, Osborne E, Taniguchi R, et al.
medRxiv
. 2020 Aug;
PMID: 32793919
T cells are involved in the early identification and clearance of viral infections and also support the development of antibodies by B cells. This central role for T cells makes...
9.
Nolan S, Vignali M, Klinger M, Dines J, Kaplan I, Svejnoha E, et al.
Res Sq
. 2020 Aug;
PMID: 32793896
We describe the establishment and current content of the ImmuneCODE™ database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects exposed to or infected with...
10.
Freed A, Clowes Candadai S, Sikes M, Thies J, Byers H, Dines J, et al.
J Pediatr
. 2020 Jun;
226:202-212.e1.
PMID: 32553838
Objectives: To evaluate the clinical usefulness of rapid exome sequencing (rES) in critically ill children with likely genetic disease using a standardized process at a single institution. To provide evidence...