Jennifer L Brigham
Overview
Explore the profile of Jennifer L Brigham including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
51
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0
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Recent Articles
1.
Golkowski M, Brigham J, Perera G, Romano G, Maly D, Ong S
Medchemcomm
. 2014 Mar;
5(3):363-369.
PMID: 24648882
The ability to determine structure-activity relationships (SAR) and identify cellular targets from cell lysates and tissues is of great utility for kinase inhibitor drug discovery. We describe a streamlined mass...
2.
Brigham J, Perera B, Maly D
ACS Chem Biol
. 2013 Jan;
8(4):691-9.
PMID: 23305300
Bioorthogonal ligation methods that allow the selective conjugation of fluorophores or biotin to proteins and small molecule probes that contain inert chemical handles are an important component of many chemical...
3.
Krishnamurty R, Brigham J, Leonard S, Ranjitkar P, Larson E, Dale E, et al.
Nat Chem Biol
. 2012 Nov;
9(1):43-50.
PMID: 23143416
Protein kinases, key regulators of intracellular signal transduction, have emerged as an important class of drug targets. Chemical proteomic tools that facilitate the functional interrogation of protein kinase active sites...