Jenna K Schmidt
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Explore the profile of Jenna K Schmidt including associated specialties, affiliations and a list of published articles.
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10
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15
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Recent Articles
1.
Keding L, Heselton A, Ren E, Shaw S, Koenig M, Golos T, et al.
Placenta
. 2025 Mar;
163:16-28.
PMID: 40024139
Introduction: Early primate placental development occurs within a low oxygen (O) environment, whereas in vitro differentiation of trophoblasts is performed at supraphysiologic O levels. Macaque trophoblast stem cells (TSCs) are...
2.
Schmidt J, Wilson R, Davenport B, Hacker T, Fitz C, Simmons H, et al.
Placenta
. 2024 Oct;
PMID: 39362807
Nanoparticles offer promise as a mechanism to non-invasively deliver targeted placental therapeutics. Our previous studies utilizing intraplacental administration demonstrate efficient nanoparticle uptake into placental trophoblast cells and overexpression of human...
3.
Sekulovski N, Wettstein J, Carleton A, Juga L, Taniguchi L, Ma X, et al.
Elife
. 2024 Jul;
12.
PMID: 39051990
Amniogenesis, a process critical for continuation of healthy pregnancy, is triggered in a collection of pluripotent epiblast cells as the human embryo implants. Previous studies have established that bone morphogenetic...
4.
Sekulovski N, Carleton A, Rengarajan A, Lin C, Juga L, Whorton A, et al.
bioRxiv
. 2024 Jul;
PMID: 39026707
Amniogenesis is triggered in a collection of pluripotent epiblast cells as the human embryo implants. To gain insights into the critical but poorly understood transcriptional machinery governing amnion fate determination,...
5.
Schmidt J, Wilson R, Davenport B, Hacker T, Fitz C, Simmons H, et al.
bioRxiv
. 2024 Apr;
PMID: 38645086
Highlights: Novel method to deliver therapeutics to maternal-fetal interfaceDelivery of nanoparticles to the placenta via maternal catheterization.
6.
Sekulovski N, Wettstein J, Carleton A, Juga L, Taniguchi L, Ma X, et al.
bioRxiv
. 2024 Mar;
PMID: 38496419
Amniogenesis, a process critical for continuation of healthy pregnancy, is triggered in a collection of pluripotent epiblast cells as the human embryo implants. Previous studies have established that BMP signaling...
7.
Harris R, Raveendran M, Warren W, LaDeana H, Tomlinson C, Graves-Lindsay T, et al.
Genes (Basel)
. 2023 Dec;
14(12).
PMID: 38137007
The common marmoset () is one of the most widely used nonhuman primate models of human disease. Owing to limitations in sequencing technology, early genome assemblies of this species using...
8.
Schmidt J, Jones K, Van Vleck T, Emborg M
Sci Transl Med
. 2022 Mar;
14(634):eabf4879.
PMID: 35235338
Genetic modification of the embryo or germ line of nonhuman primates is envisioned as a method to develop improved models of human disease, yet the promise of such animal models...
9.
Schmidt J, Mean K, Dusek B, Hinkle H, Puntney R, Alexander E, et al.
J Med Primatol
. 2021 Jan;
50(2):108-119.
PMID: 33469948
Background: Biomedical research has recently focused on developing new models of human disease by implementing genome-editing strategies in non-human primates (NHPs) to introduce relevant gene mutations. There is a need...
10.
Zika virus in rhesus macaque semen and reproductive tract tissues: a pilot study of acute infection†
Schmidt J, Mean K, Puntney R, Alexander E, Sullivan R, Simmons H, et al.
Biol Reprod
. 2020 Aug;
103(5):1030-1042.
PMID: 32761051
Although sexual transmission of Zika virus (ZIKV) is well-documented, the viral reservoir(s) in the male reproductive tract remains uncertain in humans and immune-intact animal models. We evaluated the presence of...