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Jeh-Jeng Wang

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Articles 73
Citations 270
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Recent Articles
1.
Reddy Mutra M, Chandana T, Wang Y, Wang J
Chem Asian J . 2024 Nov; 20(4):e202401531. PMID: 39614410
We report a metal additive-free iodine-promoted one-step structural reorganization of ynamide-ynes and simultaneous stereoselective 1,2-diiodination of the migrated alkyne to form stereospecific tetrasubstituted alkenyl diiodo-tethered indoles (E-isomer). Molecular iodine is...
2.
Gore B, Chen C, Lin P, Wang J
Org Lett . 2024 Jan; 26(3):757-762. PMID: 38231886
A dual nickel- and iridium-photocatalyzed radical cascade bicyclization reaction for the synthesis of highly complex molecular structures in an atom- and step-economic manner has been described. A series of radical...
3.
Dhandabani G, Jeyakannu P, Shih C, Abraham A, Senadi G, Wang J
J Org Chem . 2023 Dec; 89(1):719-724. PMID: 38149308
This study presents a stepwise exoselective [3 + 2] cycloaddition reaction of alkynols with ketones, leading to the synthesis of 4-methylene-1,3-dioxolane derivatives. Remarkably, without any Thorpe-Ingold induced effect, the cyclization...
4.
Huang C, Hou S, Severance S, Hwang C, Fang B, Gong M, et al.
ACS Omega . 2023 Dec; 8(48):46073-46090. PMID: 38075741
Bicyclo[6.1.0]nonyne (BCN) is one of the most commonly used cycloalkynes in strain-promoted azide-alkyne cycloaddition (SPAAC). The synthesis of BCN produces two diastereomers, -BCN and -BCN. The potential significance of the...
5.
Reddy Mutra M, Li J, Wang J
Chem Commun (Camb) . 2023 May; 59(43):6584-6587. PMID: 37183618
We synthesized tetrasubstituted olefins regioselectively and stereoselectively from ynamides and internal alkynes with sulfonyl iodides under blue LEDs in few minutes. The key features are being metal-free, easy to handle,...
6.
Gore B, Wang J
Chem Commun (Camb) . 2023 Apr; 59(39):5878-5881. PMID: 37096547
Herein we describe intramolecular cascade reactions enabling the synthesis of bridged cyclopropanes, the photoinduced energy-transfer catalysis of tethered conjugated dienes. Photocatalysis affords the efficient synthesis of complex tricyclic compounds that...
7.
Gore B, Kuo C, Wang J
Chem Commun (Camb) . 2022 Oct; 58(81):11462. PMID: 36190508
Correction for 'Visible light-assisted Ni-/Ir-catalysed atom-economic synthesis of spiro[furan-3,1'-indene] derivatives' by Babasaheb Sopan Gore , , 2022, , 4087-4090, https://doi.org/10.1039/D2CC00717G.
8.
Huang C, Chang Y, Severance S, Feng J, Hou S, Gong M, et al.
Pract Lab Med . 2022 Jul; 31:e00298. PMID: 35880118
Objectives: Butyrylcholinesterase (BChE) is an important biomarker in serum, and aberrant BChE activity indicates onset and progression of human diseases. The duration of serum storage at -80 °C may introduce...
9.
Reddy Mutra M, Li J, Chen Y, Wang J
Chemistry . 2022 May; 28(42):e202200742. PMID: 35587715
We developed time-atom economic regio- and chemoselective sulfonyl radical triggered 5-exo-dig cyclization of unactivated 1,6-enynes with sulfonyl halides under metal, additive-free reaction conditions to achieve highly substituted five-membered heterocyclic compounds....
10.
Reddy Mutra M, Wang J
Nat Commun . 2022 Apr; 13(1):2345. PMID: 35487916
The radical chemistry of ynamides has recently drawn the attention of synthetic organic chemists to the construction of various N-heterocyclic compounds. Nevertheless, the ynamide-radical chemistry remains a long-standing challenge for...