Jeffrey Yap
Overview
Explore the profile of Jeffrey Yap including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
401
Followers
0
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Recent Articles
1.
MYC-mediated resistance to trametinib and HCQ in PDAC is overcome by CDK4/6 and lysosomal inhibition
Silvis M, Silva D, Rohweder R, Schuman S, Gudipaty S, Truong A, et al.
J Exp Med
. 2023 Jan;
220(3).
PMID: 36719686
Pharmacological inhibition of KRAS>RAF>MEK1/2>ERK1/2 signaling has provided no clinical benefit to patients with pancreatic ductal adenocarcinoma (PDAC). Interestingly, combined inhibition of MEK1/2 (with trametinib [T]) plus autophagy (with chloroquine [CQ]...
2.
Abbott D, OBrien S, Farnham J, Young E, Yap J, Jones K, et al.
Cancer Med
. 2019 Nov;
8(18):7924-7930.
PMID: 31670911
Background: There are few reports of the association of other cancers with Ewing sarcoma in patients and their relatives. We use a resource combining statewide genealogy and cancer reporting to...
3.
Krajewski K, Guo M, Van Den Abbeele A, Yap J, Ramaiya N, Jagannathan J, et al.
Eur Urol
. 2011 Feb;
59(5):856-62.
PMID: 21306819
Background: Vascular endothelial growth factor (VEGF)-targeted therapy has become standard treatment for patients with metastatic renal cell cancer (mRCC). Since these therapies can induce tumor necrosis and minimal tumor shrinkage,...
4.
Masciari S, Van Den Abbeele A, Diller L, Rastarhuyeva I, Yap J, Schneider K, et al.
JAMA
. 2008 Mar;
299(11):1315-9.
PMID: 18349092
Context: Individuals with Li-Fraumeni syndrome (LFS) have an inherited cancer predisposition to a diverse array of malignancies beginning early in life; survivors of one cancer have a markedly elevated risk...
5.
Wall J, Kennel S, Paulus M, Gregor J, Richey T, Avenell J, et al.
J Nucl Med
. 2006 Dec;
47(12):2016-24.
PMID: 17138745
Unlabelled: Currently, there are no available means in the United States to document objectively the location and extent of amyloid deposits in patients with systemic forms of amyloidosis. To address...
6.
Shankar L, Hoffman J, Bacharach S, Graham M, Karp J, Lammertsma A, et al.
J Nucl Med
. 2006 Jun;
47(6):1059-66.
PMID: 16741317
No abstract available.