Jeffrey Whitsett
Overview
Explore the profile of Jeffrey Whitsett including associated specialties, affiliations and a list of published articles.
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19
Citations
881
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Recent Articles
1.
Deshmukh H, Whitsett J, Zacharias W, Way S, Martinez F, Mizgerd J, et al.
Pediatr Pulmonol
. 2024 Nov;
60(1):e27357.
PMID: 39565217
Viral lower respiratory tract infections (LRTI) are ubiquitous in early life. They are disproportionately severe in infants and toddlers (0-2 years), leading to more than 100,000 hospitalizations in the United...
2.
Sikkema L, Ramirez-Suastegui C, Strobl D, Gillett T, Zappia L, Madissoon E, et al.
Nat Med
. 2023 Jun;
29(6):1563-1577.
PMID: 37291214
Single-cell technologies have transformed our understanding of human tissues. Yet, studies typically capture only a limited number of donors and disagree on cell type definitions. Integrating many single-cell datasets can...
3.
Karolak J, Welch C, Mosimann C, Bzdega K, West J, Montani D, et al.
Am J Respir Crit Care Med
. 2022 Nov;
207(7):855-864.
PMID: 36367783
Over the past decade, recognition of the profound impact of the () gene, which encodes a member of the evolutionarily conserved family of T-box-containing transcription factors, on respiratory diseases has...
4.
Taylor D, Aronow B, Tan K, Bernt K, Salomonis N, Greene C, et al.
Dev Cell
. 2019 Apr;
49(1):10-29.
PMID: 30930166
Single-cell gene expression analyses of mammalian tissues have uncovered profound stage-specific molecular regulatory phenomena that have changed the understanding of unique cell types and signaling pathways critical for lineage determination,...
5.
Gray J, Oehrle K, Worthen G, Alenghat T, Whitsett J, Deshmukh H
Sci Transl Med
. 2017 Feb;
9(376).
PMID: 28179507
Immature mucosal defenses contribute to increased susceptibility of newborn infants to pathogens. Sparse knowledge of age-dependent changes in mucosal immunity has hampered improvements in neonatal morbidity because of infections. We...
6.
Snowball J, Ambalavanan M, Whitsett J, Sinner D
Dev Biol
. 2015 Jun;
405(1):56-70.
PMID: 26093309
Tracheobronchomalacia is a common congenital defect in which the walls of the trachea and bronchi lack of adequate cartilage required for support of the airways. Deletion of Wls, a cargo...
7.
Snowball J, Ambalavanan M, Cornett B, Lang R, Whitsett J, Sinner D
Dev Biol
. 2015 Mar;
401(2):264-75.
PMID: 25727890
Midline defects account for approximately 5% of congenital abnormalities observed at birth. However, the molecular mechanisms underlying the formation of the ventral body wall are not well understood. Recent studies...
8.
Cornett B, Snowball J, Varisco B, Lang R, Whitsett J, Sinner D
Dev Biol
. 2013 Mar;
379(1):38-52.
PMID: 23523683
Wntless (Wls), a gene highly conserved across the animal kingdom, encodes for a transmembrane protein that mediates Wnt ligand secretion. Wls is expressed in developing lung, wherein Wnt signaling is...
9.
Kenchegowda D, Swamynathan S, Gupta D, Wan H, Whitsett J, Swamynathan S
Dev Biol
. 2011 May;
356(1):5-18.
PMID: 21600198
Members of the Krüppel-like family of transcription factors regulate diverse developmental processes in various organs. Previously, we have demonstrated the role of Klf4 in the mouse ocular surface. Herein, we...
10.
Daikoku T, Jackson L, Besnard V, Whitsett J, Ellenson L, Dey S
Gynecol Oncol
. 2011 May;
122(2):424-9.
PMID: 21570712
Objective: Endometrial cancer (EMC) is the most common gynecological malignancy. The etiology and the cell types that are conducive to EMC are not completely understood, provoking further studies. Our objective...