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Jeffrey Wegener

Explore the profile of Jeffrey Wegener including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 1694
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Recent Articles
1.
Vilfan I, Tsai Y, Clark T, Wegener J, Dai Q, Yi C, et al.
J Nanobiotechnology . 2013 Apr; 11:8. PMID: 23552456
Background: Zero-mode waveguides (ZMWs) are photonic nanostructures that create highly confined optical observation volumes, thereby allowing single-molecule-resolved biophysical studies at relatively high concentrations of fluorescent molecules. This principle has been...
2.
Korlach J, Bjornson K, Chaudhuri B, Cicero R, Flusberg B, Gray J, et al.
Methods Enzymol . 2010 Jun; 472:431-55. PMID: 20580975
Pacific Biosciences has developed a method for real-time sequencing of single DNA molecules (Eid et al., 2009), with intrinsic sequencing rates of several bases per second and read lengths into...
3.
Eid J, Fehr A, Gray J, Luong K, Lyle J, Otto G, et al.
Science . 2008 Nov; 323(5910):133-8. PMID: 19023044
We present single-molecule, real-time sequencing data obtained from a DNA polymerase performing uninterrupted template-directed synthesis using four distinguishable fluorescently labeled deoxyribonucleoside triphosphates (dNTPs). We detected the temporal order of their...
4.
Korlach J, Bibillo A, Wegener J, Peluso P, Pham T, Park I, et al.
Nucleosides Nucleotides Nucleic Acids . 2008 Aug; 27(9):1072-83. PMID: 18711669
We demonstrate the efficient synthesis of DNA with complete replacement of the four deoxyribonucleoside triphosphate (dNTP) substrates with nucleotides carrying fluorescent labels. A different, spectrally separable fluorescent dye suitable for...
5.
Takkellapati S, Chen C, Neschadimenko V, Nampalli S, Xiao H, Wegener J, et al.
Nucleosides Nucleotides Nucleic Acids . 2007 Dec; 26(10-12):1467-70. PMID: 18066808
Synthesis of aminomethyl and bis-aminomethylfluorescein derived energy transfer terminators is described.