Jeffrey W Ruberti
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Explore the profile of Jeffrey W Ruberti including associated specialties, affiliations and a list of published articles.
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49
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1176
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Recent Articles
1.
Oh L, Silverman A, Rossi N, Randolph M, Paten J, Siadat S, et al.
J Shoulder Elbow Surg
. 2024 Oct;
PMID: 39384013
Hypothesis: Delivery of soluble allogeneic type I telocollagen (allo-telocollagen) will accelerate and improve the healing of damaged tendons. Our hypothesis draws from known mechanochemical properties of type I collagen that...
2.
Flavin W, Hosseini H, Ruberti J, Kavehpour H, Giza C, Prins M
Front Neurol
. 2023 Aug;
14:1239653.
PMID: 37638180
Tau is a protein that has received national mainstream recognition for its potential negative impact to the brain. This review succinctly provides information on the structure of tau and its...
3.
Siadat S, Ruberti J
Acta Biomater
. 2023 Jan;
163:50-62.
PMID: 36669548
The collagen molecular family is the result of nearly one billion years of evolution. It is a unique family of proteins, the majority of which provide general mechanical support to...
4.
Siadat S, Silverman A, Susilo M, Paten J, DiMarzio C, Ruberti J
Macromol Biosci
. 2021 Dec;
22(3):e2100144.
PMID: 34856056
While de novo collagen fibril formation is well-studied, there are few investigations into the growth and remodeling of extant fibrils, where molecular collagen incorporation into and erosion from the fibril...
5.
Siadat S, Zamboulis D, Thorpe C, Ruberti J, Connizzo B
Adv Exp Med Biol
. 2021 Nov;
1348:45-103.
PMID: 34807415
In his Lissner Award medal lecture in 2000, Stephen Cowin asked the question: "How is a tissue built?" It is not a new question, but it remains as relevant today...
6.
Alzola R, Siadat S, Gajjar A, Stureborg R, Ruberti J, Delpiano J, et al.
J Biomed Opt
. 2021 Jul;
26(7).
PMID: 34240588
Significance: Collagen is the most abundant protein in vertebrates and is found in tissues that regularly experience tension, compression, and shear forces. However, the underlying mechanism of collagen fibril formation...
7.
Jamieson R, Stasiak S, Polio S, Augspurg R, McCormick C, Ruberti J, et al.
J Appl Physiol (1985)
. 2021 Apr;
130(6):1635-1645.
PMID: 33792403
The current therapeutic approach to asthma focuses exclusively on targeting inflammation and reducing airway smooth muscle force to prevent the recurrence of symptoms. However, even when inflammation is brought under...
8.
Siadat S, Silverman A, DiMarzio C, Ruberti J
J Struct Biol
. 2021 Feb;
213(1):107697.
PMID: 33545351
Collagen fibrils, linear arrangements of collagen monomers, 20-500 nm in diameter, comprising hundreds of molecules in their cross-section, are the fundamental structural unit in a variety of load-bearing tissues such...
9.
LXRs regulate features of age-related macular degeneration and may be a potential therapeutic target
Choudhary M, Ismail E, Yao P, Tayyari F, Radu R, Nusinowitz S, et al.
JCI Insight
. 2019 Dec;
5(1).
PMID: 31829999
Effective treatments and animal models for the most prevalent neurodegenerative form of blindness in elderly people, called age-related macular degeneration (AMD), are lacking. Genome-wide association studies have identified lipid metabolism...
10.
Wu P, Kabakova I, Ruberti J, Sherwood J, Dunlop I, Paterson C, et al.
Nat Methods
. 2018 Aug;
15(8):561-562.
PMID: 30065366
No abstract available.