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Jeffrey Tom

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Articles 21
Citations 702
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Recent Articles
1.
Peng L, Helgason E, Miranda R, Tom J, Zhang J, Dueber E, et al.
Bioconjug Chem . 2024 Jan; 35(2):245-253. PMID: 38236171
-Boc--(2-(tritylthio)ethoxy)glycine has been developed as a building block for peptide ubiquitination, which is fully compatible with solid-phase Fmoc chemistry and common peptide modifications including phosphorylation, methylation, acetylation, biotinylation, and fluorescence...
2.
Chan A, Sawant M, Burdick D, Tom J, Song A, Cunningham C
ACS Chem Biol . 2023 Jan; 18(1):81-90. PMID: 36607609
Advances in genetic code reprogramming have allowed the site-specific incorporation of noncanonical functionalities into polypeptides and proteins, providing access to wide swaths of chemical space via translation techniques like mRNA...
3.
Miller G, Flynn E, Tom J, Song A, Cochran A
ACS Chem Biol . 2022 Apr; 17(5):1022-1029. PMID: 35467836
Genetic code expansion has proven invaluable to the elucidation of functions of defined protein modifications through the site-specific incorporation of noncanonical amino acids. The use of nonhydrolyzable derivatives of post-translational...
4.
Decalf J, Tom J, Mai E, Hernandez-Barry H, Noland C, Vollmar B, et al.
Bioorg Chem . 2022 Feb; 120:105655. PMID: 35134644
No abstract available.
5.
Decalf J, Tom J, Mai E, Hernandez-Barry H, Noland C, Vollmar B, et al.
Bioorg Chem . 2021 Sep; 116:105376. PMID: 34560560
Antitumor immune responses depend on the infiltration of solid tumors by effector T cells, a process guided by chemokines. In particular, the chemokine CXCL10 has been shown to play a...
6.
Urwin J, Bauer R, Cunningham J, Oleksy T, Seto T, Khan Z, et al.
Healthc (Amst) . 2020 Aug; 9(3):100426. PMID: 32771486
Background: Cardiac interventions account for a significant share of overall healthcare spending and have been the focus of several large-scale interventions to develop effective bundled payments. To date, however, none...
7.
Dinh C, Linn K, Isidro U, Emanuel E, Volpp K, Bond A, et al.
J Am Coll Radiol . 2020 Jan; 17(1 Pt B):101-109. PMID: 31918865
Objective: To evaluate whether the implementation of a new population-based primary care payment system, Population-Based Payments for Primary Care (3PC), initiated by Hawaii Medical Service Association (HMSA; the Blue Cross...
8.
Yamazoe S, Tom J, Fu Y, Wu W, Zeng L, Sun C, et al.
J Med Chem . 2019 Dec; 63(6):2807-2813. PMID: 31874036
Heterobifunctional molecules have proven powerful tools to induce ligase-dependent ubiquitination of target proteins. We describe here a chemical strategy for controlling a different post-translational modification (PTM): phosphorylation. Heterobifunctional molecules were...
9.
Navathe A, Emanuel E, Bond A, Linn K, Caldarella K, Troxel A, et al.
JAMA . 2019 Jul; 322(1):57-68. PMID: 31265101
Importance: Hawaii Medical Service Association (HMSA), the Blue Cross Blue Shield of Hawaii, introduced Population-based Payments for Primary Care (3PC), a new capitation-based primary care payment system, in 2016. The...
10.
Smith D, OKeeffe-Rosetti M, Owen-Smith A, Rand C, Tom J, Vupputuri S, et al.
Value Health . 2016 Mar; 19(2):176-84. PMID: 27021751
Objective: Preplanned economic analysis of a pragmatic trial using electronic-medical-record-linked interactive voice recognition (IVR) reminders for enhancing adherence to cardiovascular medications (i.e., statins, angiotensin-converting enzyme inhibitors [ACEIs], and angiotensin receptor...