Jeffrey S Kavanaugh
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Explore the profile of Jeffrey S Kavanaugh including associated specialties, affiliations and a list of published articles.
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1253
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Recent Articles
1.
Hook J, Matheis A, Kavanaugh J, Horswill A, Moreland J
Inflammation
. 2024 Sep;
PMID: 39302496
Neutrophils, polymorphonuclear leukocytes (PMN), express numerous pattern recognition receptors, including TLRs, capable of recognizing a wide variety of pathogens. Receptor engagement initiates a cascade of PMN responses with some occurring...
2.
Langouet-Astrie C, Oshima K, McMurtry S, Yang Y, Kwiecinski J, LaRiviere W, et al.
Cell Rep
. 2022 Nov;
41(9):111721.
PMID: 36450248
Influenza infection is substantially worsened by the onset of secondary pneumonia caused by bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA). The bidirectional interaction between the influenza-injured lung microenvironment and MRSA...
3.
Keogh R, Haeberle A, Langouet-Astrie C, Kavanaugh J, Schmidt E, Moore G, et al.
Sci Adv
. 2022 Nov;
8(45):eadd3221.
PMID: 36367946
Diabetic wounds have poor healing outcomes due to the presence of numerous pathogens and a dysregulated immune response. Group B (GBS) is commonly isolated from diabetic wound infections, but the...
4.
Haynes A, Prinzi A, Silveira L, Parker S, Lampe J, Kavanaugh J, et al.
Microbiol Spectr
. 2022 Jun;
10(4):e0103922.
PMID: 35730963
Cephalexin and cefadroxil are oral first-generation cephalosporins used to treat methicillin-susceptible Staphylococcus aureus (MSSA) infections. Despite its shorter half-life, cephalexin is more frequently prescribed, although cefadroxil is an appealing alternative,...
5.
de Vor L, Dijk B, van Kessel K, Kavanaugh J, de Haas C, Aerts P, et al.
Elife
. 2022 Jan;
11.
PMID: 34989676
Implant-associated infections are difficult to treat because of biofilm formation. Bacteria in a biofilm are often insensitive to antibiotics and host immunity. Monoclonal antibodies (mAbs) could provide an alternative approach...
6.
Hook J, Patel P, OMalley A, Xie L, Kavanaugh J, Horswill A, et al.
J Immunol
. 2021 Jul;
207(3):966-973.
PMID: 34290104
Neutrophils, polymorphonuclear leukocytes (PMN), play a critical role in the innate immune response to , a pathogen that continues to be associated with significant morbidity and mortality. Neutrophil extracellular trap...
7.
Kavanaugh J, Leidal K, Nauseef W, Horswill A
J Infect Dis
. 2020 Sep;
223(11):1865-1869.
PMID: 32995850
Polymorphonuclear leukocytes (PMN) phagocytose and kill individual bacteria but are far less efficient when challenged with bacterial aggregates. Consequently, growth within a biofilm affords Staphylococcus aureus some protection but PMN...
8.
Cau L, Williams M, Butcher A, Nakatsuji T, Kavanaugh J, Cheng J, et al.
J Allergy Clin Immunol
. 2020 Jul;
147(3):955-966.e16.
PMID: 32634452
Background: Staphylococcus aureus and Staphylococcus epidermidis are the most abundant bacteria found on the skin of patients with atopic dermatitis (AD). S aureus is known to exacerbate AD, whereas S...
9.
Grundstad M, Parlet C, Kwiecinski J, Kavanaugh J, Crosby H, Cho Y, et al.
mSphere
. 2019 Aug;
4(4).
PMID: 31413175
Methicillin-resistant (MRSA) infections impact all patient populations both in the community and in health care settings. Despite advances in our knowledge of MRSA virulence, little is known about the regulatory...
10.
Kavanaugh J, Flack C, Lister J, Ricker E, Ibberson C, Jenul C, et al.
mBio
. 2019 Jun;
10(3).
PMID: 31239382
We developed a new approach that couples Southwestern blotting and mass spectrometry to discover proteins that bind extracellular DNA (eDNA) in bacterial biofilms. Using as a model pathogen, we identified...