Jeffrey L Cummings
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Explore the profile of Jeffrey L Cummings including associated specialties, affiliations and a list of published articles.
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311
Citations
25530
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Recent Articles
1.
Zhan H, Cammann D, Cummings J, Dong X, Chen J
J Transl Med
. 2025 Mar;
23(1):278.
PMID: 40050982
Background: Alzheimer's disease (AD) is the main cause of dementia with few effective therapies. We aimed to identify potential plasma biomarkers or drug targets for AD by investigating the causal...
2.
Cummings J, Zhou Y, Van Stone A, Cammann D, Tonegawa-Kuji R, Fonseca J, et al.
Nat Commun
. 2025 Feb;
16(1):1755.
PMID: 39971900
Repurposed drugs provide a rich source of potential therapies for Alzheimer's disease (AD) and other neurodegenerative disorders (NDD). Repurposed drugs have information from non-clinical studies, phase 1 dosing, and safety...
3.
Leisgang Osse A, Kinney J, Cummings J
Alzheimers Dement (N Y)
. 2025 Feb;
11(1):e70050.
PMID: 39935614
Highlights: The Common Alzheimer's Disease Research Ontology (CADRO) system can be used to categorize biomarkers for drug development.We demonstrate the use of CADRO with Alzheimer's disease (AD) biomarkers.We identified AD...
4.
Altaras C, Ly M, Schultz O, Barr W, Banks S, Wethe J, et al.
Clin Neuropsychol
. 2025 Jan;
:1-29.
PMID: 39865747
Exposure to repetitive head impacts (RHI), such as those experienced in American football, is linked to cognitive dysfunction later in life. Traumatic encephalopathy syndrome (TES) is a proposed clinical syndrome...
5.
Ly M, Altaras C, Tripodis Y, Adler C, Balcer L, Bernick C, et al.
Clin Neuropsychol
. 2025 Jan;
:1-25.
PMID: 39834028
Cognitive impairment is a core feature of traumatic encephalopathy syndrome (TES), the putative clinical syndrome of chronic traumatic encephalopathy-a neuropathological disease associated with repetitive head impacts (RHI). Careful operationalization of...
6.
Alexander R, Reiman E, Cummings J, Langbaum J, Mattke S
Clin Neurol Neurosurg
. 2025 Jan;
249:108735.
PMID: 39809096
No abstract available.
7.
Cummings J, Atri A, Feldman H, Hansson O, Sano M, Knop F, et al.
Alzheimers Res Ther
. 2025 Jan;
17(1):14.
PMID: 39780249
Background: Disease-modifying therapies targeting the diverse pathophysiology of Alzheimer's disease (AD), including neuroinflammation, represent potentially important and novel approaches. The glucagon-like peptide-1 receptor agonist semaglutide is approved for the treatment...
8.
Lansdall C, Cummings J, Andrews J
Alzheimers Dement
. 2024 Dec;
21(2):e14436.
PMID: 39692602
No abstract available.
9.
Cummings J, Brubaker M, Selzler K, Gonzalez S, Patel M, Stahl S
CNS Spectr
. 2024 Oct;
:1-10.
PMID: 39438777
Alzheimer's dementia (AD) is a progressive, neurodegenerative disease often accompanied by neuropsychiatric symptoms that profoundly impact both patients and caregivers. Agitation is among the most prevalent and distressing of these...
10.
Miner A, Groh J, Tripodis Y, Adler C, Balcer L, Bernick C, et al.
Alzheimers Dement
. 2024 Oct;
20(11):7529-7546.
PMID: 39351900
Introduction: Blood-based biomarkers offer a promising approach for the detection of neuropathologies from repetitive head impacts (RHI). We evaluated plasma biomarkers of amyloid, tau, neurodegeneration, and inflammation in former football...