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Jeffrey H Boatright

Explore the profile of Jeffrey H Boatright including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 1076
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Recent Articles
1.
Lin F, Lin S, Wang J, Sellers J, Chrenek M, Nickerson J, et al.
Mol Vis . 2025 Mar; 31:1-9. PMID: 40084287
Purpose: Intravitreal injection of adeno-associated virus (AAV) vectors is a good approach for transducing retinal ganglion cells (RGCs) in mice. It allows for high transduction efficiency and is relatively specific...
2.
Haupt H, Nickerson J, Boatright J, Pardue M, Bales K
bioRxiv . 2025 Feb; PMID: 39990328
Purpose: Exercise is neuroprotective in rodents undergoing retinal degeneration (RD). However, the effects of exercise on retinal vasculature remain unexplored. Here, we investigate whether treadmill exercise influences retinal vascular morphology,...
3.
Aliff H, Crockett A, Chrenek M, Nickerson J, Boatright J, Tseytlin O, et al.
Invest Ophthalmol Vis Sci . 2025 Feb; 66(2):49. PMID: 39969479
Purpose: To design and validate a cost-effective and titratable system capable of light-induced photoreceptor dysfunction and damage in pigmented mice. Methods: Two commonly used mouse strains in vision research, C57BL/6J...
4.
Phillips S, Feola A, Solomon J, Cardelle L, Douglass A, Bales K, et al.
Mol Vis . 2025 Feb; 30:239-259. PMID: 39959182
While the high-dose streptozotocin (STZ; 100 mg/kg) rodent model is the gold standard in modeling Type I diabetes, models for Type II diabetes are needed for this more common form...
5.
Shelton D, Papania J, Getz T, Sellers J, Giradot P, Chrenek M, et al.
bioRxiv . 2024 Dec; PMID: 39679905
Purpose: Pigment epithelium-derived factor (PEDF) is a neurotrophic glycoprotein secreted by the retinal pigment epithelium (RPE) that supports retinal photoreceptor health. Deficits in PEDF are associated with increased inflammation and...
6.
Donaldson K, Donaldson K, Chrenek M, Boatright J, Nickerson J
bioRxiv . 2024 Dec; PMID: 39677811
The retinal pigment epithelium (RPE), a monolayer of pigmented cells, is critical for visual function through its interaction with the neural retina. In healthy eyes, RPE cells exhibit a uniform...
7.
Zhang N, Li Y, Zhang X, Chrenek M, Wang J, Girardot P, et al.
bioRxiv . 2024 Dec; PMID: 39677633
Purpose: The aim of this study was to test whether oral administration of nicotinamide riboside (NR), the nicotinamide adenine dinucleotide (NAD+) precursors, protect retina ganglion cells (RGCs) from neurodegeneration in...
8.
Markand S, Kim S, Chrenek M, Ferdous S, Priyadarshani P, Boatright J, et al.
Curr Eye Res . 2024 Sep; 50(2):221-230. PMID: 39314009
Purpose: Myopia is a complex disorder with etiology involving an interplay between several genetic and environmental factors. Interphotoreceptor retinoid-binding protein (IRBP) is found in the subretinal space and is crucial...
9.
Getz T, Chrenek M, Papania J, Shelton D, Markand S, Iuvone P, et al.
Invest Ophthalmol Vis Sci . 2024 Jun; 65(6):32. PMID: 38904640
Purpose: Interphotoreceptor retinoid-binding protein's (IRBP) role in eye growth and its involvement in cell homeostasis remain poorly understood. One hypothesis proposes early conditional deletion of the IRBP gene could lead...
10.
Lin F, Li Y, Wang J, Jardines S, King R, Chrenek M, et al.
Sci Rep . 2024 May; 14(1):10096. PMID: 38698014
Pou6f2 is a genetic connection between central corneal thickness (CCT) in the mouse and a risk factor for developing primary open-angle glaucoma. POU6F2 is also a risk factor for several...