Jeffrey E Quigley
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Explore the profile of Jeffrey E Quigley including associated specialties, affiliations and a list of published articles.
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8
Citations
437
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Recent Articles
1.
Manhiani M, Quigley J, Knight S, Tasoobshirazi S, Moore T, Brands M, et al.
Am J Physiol Renal Physiol
. 2009 Jun;
297(3):F740-8.
PMID: 19553349
Inhibition of soluble epoxide hydrolase (sEH) has been shown to be renal protective in rat models of salt-sensitive hypertension. Here, we hypothesize that targeted disruption of the sEH gene (Ephx2)...
2.
Quigley J, Elmarakby A, Knight S, Manhiani M, Stepp D, Olearzcyk J, et al.
Clin Exp Pharmacol Physiol
. 2009 Feb;
36(7):724-8.
PMID: 19207724
1. In the present study, we determined the role of hypertension, oxidative stress and inflammation on kidney damage in a rodent model of obesity and diabetes. Hypertension was induced in...
3.
Olearczyk J, Quigley J, Mitchell B, Yamamoto T, Kim I, Newman J, et al.
Clin Sci (Lond)
. 2008 May;
116(1):61-70.
PMID: 18459944
Hypertension and Type 2 diabetes are co-morbid diseases that lead to the development of nephropathy. sEH (soluble epoxide hydrolase) inhibitors are reported to provide protection from renal injury. We hypothesized...
4.
Knight S, Quigley J, Yuan J, Roy S, Elmarakby A, Imig J
Hypertension
. 2007 Dec;
51(2):352-9.
PMID: 18158349
Obesity and hypertension have been identified as cardiovascular risk factors that contribute to the progression of end-stage renal disease. To examine the mechanisms by which a high-fat diet and hypertension...
5.
Elmarakby A, Quigley J, Imig J, Pollock J, Pollock D
Am J Physiol Regul Integr Comp Physiol
. 2007 Nov;
294(1):R76-83.
PMID: 17989143
Studies suggest that the inflammatory cytokine TNF-alpha plays a role in the prognosis of end-stage renal diseases. We previously showed that TNF-alpha inhibition slowed the progression of hypertension and renal...
6.
Elmarakby A, Quigley J, Olearczyk J, Sridhar A, Cook A, Inscho E, et al.
Hypertension
. 2007 Oct;
50(6):1069-76.
PMID: 17938380
The present study was designed to determine whether chemokine receptor 2b (CCR2b) contributes to the development of renal injury in salt-sensitive angiotensin II (ANG) hypertension. Rats were infused with ANG...
7.
Zhao X, Quigley J, Yuan J, Wang M, Zhou Y, Imig J
Am J Physiol Heart Circ Physiol
. 2006 Feb;
290(6):H2187-95.
PMID: 16501022
Previous studies have shown that the synthesis of renal cytochrome P-450 (CYP)-derived eicosanoids is downregulated in genetic or high-fat diet-induced obese rats. Experiments were designed to determine whether fenofibrate, a...
8.
Elmarakby A, Quigley J, Pollock D, Imig J
Hypertension
. 2006 Jan;
47(3):557-62.
PMID: 16415373
We hypothesized that the downregulation of Cyp2c by tumor necrosis factor (TNF) alpha contributes to hypertension and renal injury in salt-sensitive angiotensin hypertension. Male Sprague-Dawley rats were fed a high-salt...