Jeffrey B Eells
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Explore the profile of Jeffrey B Eells including associated specialties, affiliations and a list of published articles.
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Citations
272
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Recent Articles
1.
Theobald D, de Castro Braz L, Akula S, Eells J, Sriramula S
Am J Physiol Heart Circ Physiol
. 2025 Feb;
328(3):H711-H718.
PMID: 39982452
Long COVID has been associated with significant cardiovascular complications, including fibrosis, functional impairment, and chronic inflammatory and immune responses. However, the underlying mechanisms driving these cardiac pathologies following COVID-19 infection...
2.
Bauer A, Williams J, Pokhrel L, Garcia S, Majumdar N, Eells J, et al.
Toxics
. 2024 Jul;
12(7).
PMID: 39058147
Smart Nano-enabled Antiviral Therapeutic (SNAT) is a promising nanodrug that previously demonstrated efficacy in preclinical studies to alleviate SARS-CoV-2 pathology in hamsters. SNAT comprises taxoid (Tx)-decorated amino (NH)-functionalized near-atomic size...
3.
Sriramula S, Theobald D, Parekh R, Akula S, ORourke D, Eells J
Cells
. 2023 Aug;
12(16).
PMID: 37626917
Evidence suggests that patients with long COVID can experience neuropsychiatric, neurologic, and cognitive symptoms. However, these clinical data are mostly associational studies complicated by confounding variables, thus the mechanisms responsible...
4.
Fernandez R, Wilson E, Diaz V, Martinez-Gardeazabal J, Foguth R, Cannon J, et al.
J Neurochem
. 2023 Feb;
165(3):379-390.
PMID: 36815399
Dietary lipids, particularly omega-3 polyunsaturated fatty acids, are speculated to impact behaviors linked to the dopaminergic system, such as movement and control of circadian rhythms. However, the ability to draw...
5.
Smeyne R, Eells J, Chatterjee D, Byrne M, Akula S, Sriramula S, et al.
Mov Disord
. 2022 May;
37(7):1394-1404.
PMID: 35579496
Background: Viral induction of neurological syndromes has been a concern since parkinsonian-like features were observed in patients diagnosed with encephalitis lethargica subsequent to the 1918 influenza pandemic. Given the similarities...
6.
Parekh R, White A, Leffler K, Biancardi V, Eells J, Abdel-Rahman A, et al.
Sci Rep
. 2021 Oct;
11(1):21050.
PMID: 34702886
Brain orexin system hyperactivity contributes to neurogenic hypertension. We previously reported upregulated neuronal kinin B1 receptor (B1R) expression in hypertension. However, the role of central B1R activation on the orexin...
7.
Fernandez R, Pereyra A, Diaz V, Wilson E, Litwa K, Martinez-Gardeazabal J, et al.
JCI Insight
. 2021 Jun;
6(11).
PMID: 34100386
The omega-3 fatty acid docosahexaenoic acid (DHA) inversely relates to neurological impairments with aging; however, limited nondietary models manipulating brain DHA have hindered a direct linkage. We discovered that loss...
8.
Kummari E, Guo-Ross S, Partington H, Nutter J, Eells J
Front Neuroanat
. 2021 May;
15:563854.
PMID: 33994958
The transcription factor Nurr1 is a member of the steroid hormone nuclear receptor superfamily. Ablation of Nurr1 expression arrests mesencephalic dopamine neuron differentiation while attenuation of Nurr1 in the subiculum...
9.
Partington H, Nutter J, Eells J
Behav Brain Res
. 2021 May;
411:113347.
PMID: 33991560
Neurological and neuropsychiatric disorders, including addiction, schizophrenia, and Parkinson's disease (PD), involve dysfunction in midbrain dopamine (DA) neurotransmission with severity of disease symptoms and progression associated with disrupted circadian rhythms....
10.
Kummari E, Guo-Ross S, Eells J
Neurochem Neuropharmacol
. 2017 Oct;
3(1).
PMID: 28989991
The transcription factor Nurr1 is essential for dopamine neuron differentiation and is important in maintaining dopamine synthesis and neurotransmission in the adult. Reduced Nurr1 function, due to the Nurr1-null heterozygous...