Jeff Sekelsky
Overview
Explore the profile of Jeff Sekelsky including associated specialties, affiliations and a list of published articles.
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Articles
54
Citations
1192
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Recent Articles
1.
Pazhayam N, Sagar S, Sekelsky J
Genetics
. 2025 Feb;
PMID: 39996709
The centromere effect (CE) is a meiotic phenomenon that ensures meiotic crossover suppression in pericentromeric regions. Despite being a critical safeguard against nondisjunction, the mechanisms behind the CE remain unknown....
2.
Bereda C, Dewey E, Nasr M, Chirasani V, Sekelsky J
Genetics
. 2025 Jan;
PMID: 39792594
Bloom Syndrome helicase (Blm) is a RecQ family helicase involved in DNA repair, cell-cycle progression, and development. Pathogenic variants in human BLM cause the autosomal recessive disorder Bloom Syndrome, characterized...
3.
Pazhayam N, Sagar S, Sekelsky J
bioRxiv
. 2025 Jan;
PMID: 39763933
The centromere effect (CE) is a meiotic phenomenon that ensures meiotic crossover suppression in pericentromeric regions. Despite being a critical safeguard against nondisjunction, the mechanisms behind the CE remain unknown....
4.
Hawley R, Salz H, McKim K, Sekelsky J
Chromosoma
. 2024 Sep;
133(4):247-251.
PMID: 39325143
No abstract available.
5.
Bereda C, Dewey E, Nasr M, Sekelsky J
bioRxiv
. 2024 Apr;
PMID: 38659896
Bloom Syndrome helicase (Blm) is a RecQ family helicase involved in DNA repair, cell-cycle progression, and development. Pathogenic variants in human cause the autosomal recessive disorder Bloom Syndrome, characterized by...
6.
Pazhayam N, Frazier L, Sekelsky J
Genetics
. 2023 Dec;
226(3).
PMID: 38150397
Accurate segregation of homologous chromosomes during meiosis depends on both the presence and the regulated placement of crossovers (COs). The centromere effect, or CO exclusion in pericentromeric regions of the...
7.
Kose C, Cao X, Dewey E, Malkoc M, Adebali O, Sekelsky J, et al.
Nucleic Acids Res
. 2023 Nov;
52(2):677-689.
PMID: 37994737
After reconstitution of nucleotide excision repair (excision repair) with XPA, RPA, XPC, TFIIH, XPF-ERCC1 and XPG, it was concluded that these six factors are the minimal essential components of the...
8.
Pazhayam N, Frazier L, Sekelsky J
bioRxiv
. 2023 Oct;
PMID: 37905008
Accurate segregation of homologous chromosomes during meiosis depends on both the presence and regulated placement of crossovers (COs). The centromere effect (CE), or CO exclusion in pericentromeric regions of the...
9.
Gonzalez-Marin B, Calderon-Segura M, Sekelsky J
Toxics
. 2023 Sep;
11(9).
PMID: 37755764
DNA damage response (DDR) pathways in keto-enol genotoxicity have not been characterized, and few studies have reported genotoxic effects in non-target organisms. The present study shows that concentrations of 11.2,...
10.
Dewey E, Holsclaw J, Saghaey K, Wittmer M, Sekelsky J
Genetics
. 2022 Oct;
223(1).
PMID: 36303322
Proper repair of DNA double-strand breaks is essential to the maintenance of genomic stability and avoidance of genetic disease. Organisms have many ways of repairing double-strand breaks, including the use...