Jeff OConnell
Overview
Explore the profile of Jeff OConnell including associated specialties, affiliations and a list of published articles.
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12
Citations
1143
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Recent Articles
1.
Taub M, Conomos M, Keener R, Iyer K, Weinstock J, Yanek L, et al.
Cell Genom
. 2022 May;
2(1).
PMID: 35530816
Genetic studies on telomere length are important for understanding age-related diseases. Prior GWAS for leukocyte TL have been limited to European and Asian populations. Here, we report the first sequencing-based...
2.
Wang H, Noordam R, Cade B, Schwander K, Winkler T, Lee J, et al.
Mol Psychiatry
. 2021 Apr;
26(11):6293-6304.
PMID: 33859359
Long and short sleep duration are associated with elevated blood pressure (BP), possibly through effects on molecular pathways that influence neuroendocrine and vascular systems. To gain new insights into the...
3.
Bruce H, Kochunov P, Chiappelli J, Savransky A, Carino K, Sewell J, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2021 Mar;
186(2):113-121.
PMID: 33650257
Sleep is essential to the human brain and is regulated by genetics with many features conserved across species. Sleep is also influenced by health and environmental factors; identifying replicable genetic...
4.
Bagheri M, Tiwari H, Murillo A, Al-Tobasei R, Arnett D, Kind T, et al.
Lipids Health Dis
. 2020 Jun;
19(1):153.
PMID: 32586392
Background: The lipoprotein insulin resistance (LPIR) score was shown to predict insulin resistance (IR) and type 2 diabetes (T2D) in healthy adults. However, the molecular basis underlying the LPIR utility...
5.
de las Fuentes L, Sung Y, Noordam R, Winkler T, Feitosa M, Schwander K, et al.
Mol Psychiatry
. 2020 May;
26(6):2111-2125.
PMID: 32372009
Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci,...
6.
Noordam R, Bos M, Wang H, Winkler T, Bentley A, Kilpelainen T, et al.
Nat Commun
. 2019 Nov;
10(1):5121.
PMID: 31719535
Both short and long sleep are associated with an adverse lipid profile, likely through different biological pathways. To elucidate the biology of sleep-associated adverse lipid profile, we conduct multi-ancestry genome-wide...
7.
Kilpelainen T, Bentley A, Noordam R, Sung Y, Schwander K, Winkler T, et al.
Nat Commun
. 2019 Jan;
10(1):376.
PMID: 30670697
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity,...
8.
Raheja U, Fuchs D, Lowry C, Stephens S, Pavlovich M, Mohyuddin H, et al.
J Neuroimmunol
. 2017 May;
307:37-41.
PMID: 28495136
Background: We examined the heritability of neopterin, a biomarker for cell-mediated immunity and oxidative stress, and potentially for psychiatric disorders, in the Old Order Amish. Methods: Plasma neopterin levels were...
9.
Manning A, Hivert M, Scott R, Grimsby J, Bouatia-Naji N, Chen H, et al.
Nat Genet
. 2012 May;
44(6):659-69.
PMID: 22581228
Recent genome-wide association studies have described many loci implicated in type 2 diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the understanding of the genetic basis of...
10.
Murabito J, White C, Kavousi M, Sun Y, Feitosa M, Nambi V, et al.
Circ Cardiovasc Genet
. 2011 Dec;
5(1):100-12.
PMID: 22199011
Background: Genetic determinants of peripheral arterial disease (PAD) remain largely unknown. To identify genetic variants associated with the ankle-brachial index (ABI), a noninvasive measure of PAD, we conducted a meta-analysis...