Jeff Nivala
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Explore the profile of Jeff Nivala including associated specialties, affiliations and a list of published articles.
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29
Citations
701
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Recent Articles
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Zhang K, Chen Y, Wilde D, Doroschak K, Strauss K, Ceze L, et al.
Nat Commun
. 2022 Aug;
13(1):4904.
PMID: 35987925
DNA has emerged as a powerful substrate for programming information processing machines at the nanoscale. Among the DNA computing primitives used today, DNA strand displacement (DSD) is arguably the most...
13.
Bhattarai-Kline S, Lear S, Fishman C, Lopez S, Lockshin E, Schubert M, et al.
Nature
. 2022 Jul;
608(7921):217-225.
PMID: 35896746
Biological processes depend on the differential expression of genes over time, but methods to make physical recordings of these processes are limited. Here we report a molecular system for making...
14.
Meiser L, Nguyen B, Chen Y, Nivala J, Strauss K, Ceze L, et al.
Nat Commun
. 2022 Jan;
13(1):352.
PMID: 35039502
Synthetic DNA is a growing alternative to electronic-based technologies in fields such as data storage, product tagging, or signal processing. Its value lies in its characteristic attributes, namely Watson-Crick base...
15.
Motone K, Cardozo N, Nivala J
iScience
. 2021 Sep;
24(9):103032.
PMID: 34527891
Proteins carry out life's essential functions. Comprehensive proteome analysis technologies are thus required for a full understanding of the operating principles of biological systems. While current proteomics techniques suffer from...
16.
Cardozo N, Zhang K, Doroschak K, Nguyen A, Siddiqui Z, Bogard N, et al.
Nat Biotechnol
. 2021 Aug;
40(1):42-46.
PMID: 34385692
Detection of specific proteins using nanopores is currently challenging. To address this challenge, we developed a collection of over twenty nanopore-addressable protein tags engineered as reporters (NanoporeTERs, or NTERs). NTERs...
17.
Palla M, Punthambaker S, Stranges B, Vigneault F, Nivala J, Wiegand D, et al.
ACS Nano
. 2020 Dec;
15(1):489-502.
PMID: 33370106
DNA polymerases have revolutionized the biotechnology field due to their ability to precisely replicate stored genetic information. Screening variants of these enzymes for specific properties gives the opportunity to identify...
18.
Doroschak K, Zhang K, Queen M, Mandyam A, Strauss K, Ceze L, et al.
Nat Commun
. 2020 Nov;
11(1):5454.
PMID: 33144581
Molecular tagging is an approach to labeling physical objects using DNA or other molecules that can be used when methods such as RFID tags and QR codes are unsuitable. No...
19.
Nivala J, Mulroney L, Luan Q, Abu-Shumays R, Akeson M
Methods Mol Biol
. 2020 Sep;
2186:145-155.
PMID: 32918735
Proteins present a significant challenge for nanopore-based sequence analysis. This is partly due to their stable tertiary structures that must be unfolded for linear translocation, and the absence of regular...
20.