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Jeanette Seiler

Explore the profile of Jeanette Seiler including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 644
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Recent Articles
11.
Caudron-Herger M, Pankert T, Seiler J, Nemeth A, Voit R, Grummt I, et al.
EMBO J . 2015 Oct; 34(22):2758-74. PMID: 26464461
Non-coding RNAs play a key role in organizing the nucleus into functional subcompartments. By combining fluorescence microscopy and RNA deep-sequencing-based analysis, we found that RNA polymerase II transcripts originating from...
12.
Voit R, Seiler J, Grummt I
PLoS Genet . 2015 May; 11(5):e1005246. PMID: 26023773
Mitotic repression of rRNA synthesis requires inactivation of the RNA polymerase I (Pol I)-specific transcription factor SL1 by Cdk1/cyclin B-dependent phosphorylation of TAF(I)110 (TBP-associated factor 110) at a single threonine...
13.
Chen S, Seiler J, Santiago-Reichelt M, Felbel K, Grummt I, Voit R
Mol Cell . 2013 Nov; 52(3):303-13. PMID: 24207024
Sirtuins are NAD(+)-dependent protein deacetylases that connect metabolism and cellular homeostasis. Here we show that the nuclear Sirtuin SIRT7 targets PAF53, a subunit of RNA polymerase I (Pol I). Acetylation...
14.
McGillicuddy L, Fromm J, Hollstein P, Kubek S, Beroukhim R, De Raedt T, et al.
Cancer Cell . 2009 Jul; 16(1):44-54. PMID: 19573811
Loss-of-function mutations in the NF1 tumor suppressor result in deregulated Ras signaling and drive tumorigenesis in the familial cancer syndrome neurofibromatosis type I. However, the extent to which NF1 inactivation...
15.
Hothorn M, Neumann H, Lenherr E, Wehner M, Rybin V, Hassa P, et al.
Science . 2009 Apr; 324(5926):513-6. PMID: 19390046
Polyphosphate (polyP) occurs ubiquitously in cells, but its functions are poorly understood and its synthesis has only been characterized in bacteria. Using x-ray crystallography, we identified a eukaryotic polyphosphate polymerase...
16.
Peset I, Seiler J, Sardon T, Bejarano L, Rybina S, Vernos I
J Cell Biol . 2005 Sep; 170(7):1057-66. PMID: 16172207
The Xenopus protein Maskin has been previously identified and characterized in the context of its role in translational control during oocyte maturation. Maskin belongs to the TACC protein family. In...
17.
Sunder-Plassmann N, Sarli V, Gartner M, Utz M, Seiler J, Huemmer S, et al.
Bioorg Med Chem . 2005 Aug; 13(22):6094-111. PMID: 16084101
The mitotic kinesin Eg5 (or KSP) is a crucial player in the development and function of the mitotic spindle. Inhibition of this protein leads to cell cycle arrest and apoptosis...
18.
Gartner M, Sunder-Plassmann N, Seiler J, Utz M, Vernos I, Surrey T, et al.
Chembiochem . 2005 May; 6(7):1173-7. PMID: 15912555
No abstract available.