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Jean Hou

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Articles 44
Citations 867
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Recent Articles
1.
Mongalo M, Diaz V, Kim A, Hou J, Bourji K
Cureus . 2024 Sep; 16(8):e66202. PMID: 39233988
Tubulointerstitial nephritis and uveitis (TINU) syndrome is an uncommon autoimmune disorder that is defined by tubulointerstitial nephritis and uveitis. It is frequently underdiagnosed or goes unrecognized due to the challenges...
2.
Elliott M, Vena N, Marasa M, Cocchi E, Bheda S, Bogyo K, et al.
J Clin Invest . 2024 Sep; 134(17). PMID: 39225089
BACKGROUNDIt is unknown whether the risk of kidney disease progression and failure differs between patients with and without genetic kidney disorders.METHODSThree cohorts were evaluated: the prospective Cure Glomerulonephropathy Network (CureGN)...
3.
Grace Choung H, Nast C, Haas M, Lin M, Yamashita M, Hou J
Kidney Int Rep . 2024 Jul; 9(7):2180-2188. PMID: 39081731
Introduction: Methamphetamine (METH) is one of the most used drugs of abuse worldwide. However, there are few reports and series examining the toxic kidney effects of METH, and associated histopathological...
4.
Andeen N, Hou J
Pediatr Dev Pathol . 2024 Apr; 27(5):387-410. PMID: 38576387
Recent progress in glomerular immune complex and complement-mediated diseases have refined diagnostic categories and informed mechanistic understanding of disease development in pediatric patients. Herein, we discuss selected advances in 3...
5.
Aggarwal S, Wang Z, Pacheco D, Rinaldi A, Rajewski A, Callemeyn J, et al.
Science . 2024 Feb; 383(6685):eadd6371. PMID: 38386758
The steps governing healing with or without fibrosis within the same microenvironment are unclear. After acute kidney injury (AKI), injured proximal tubular epithelial cells activate SOX9 for self-restoration. Using a...
6.
Barbour S, Coppo R, Er L, Pillebout E, Russo M, Alpers C, et al.
Clin J Am Soc Nephrol . 2024 Jan; 19(4):438-451. PMID: 38261310
Background: Nephritis is a common manifestation of IgA vasculitis and is morphologically indistinguishable from IgA nephropathy. While MEST-C scores are predictive of kidney outcomes in IgA nephropathy, their value in...
7.
Palmer M, Royal V, Jennette J, Smith A, Liu Q, Ambruzs J, et al.
Glomerular Dis . 2023 Nov; 3(1):248-257. PMID: 38021464
Introduction: Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,...
8.
Leong M, Sathi B, Davis A, Hamid S, Wu S, Woods J, et al.
J Pediatr Endocrinol Metab . 2023 Nov; 36(12):1186-1190. PMID: 37979187
Objectives: Alpha-mannosidosis is a rare genetic lysosomal storage condition leading to the systemic buildup of oligomannoside. Clinical presentation and associated conditions, as well as the full extent of histopathologic changes...
9.
Ren K, Hou J
Glomerular Dis . 2023 Oct; 3(1):197-210. PMID: 37901699
Introduction: Membranous nephropathy (MN) is a common cause of adult nephrotic syndrome in the USA. The typical ultrastructural finding is of global uniformly dense subepithelial electron-dense immune complex deposits along...
10.
Pahl M, Hou J
Glomerular Dis . 2023 Oct; 3(1):189-196. PMID: 37901696
Background: Fabry disease (FD) is an X-linked disorder due to a pathogenic variant of the gene that codes for the alpha-galactosidase enzyme. The reduced or absent activity of the enzyme...